NASP implication in the androgen receptor associated with castration resistance in prostate cancer

NASP implication in the androgen receptor associated with castration resistance in prostate cancer

Abstract Uncovering the mechanisms underlying tumor malignancy is extremely important for cancer treatment and management. In this study, using a pairwise cell model, LNCaP and its castration-resistant derivative C42B, we analyze the function of enhanced NASP protein in castration resistance. The da...

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Bibliographic Details
Main Authors: Yun Feng, Jin Sun, Xuan Kang, Yining Wang, Kai Liu, Wenfei Wang, Chen Wang, Yabin Li, Qian Zhao, Kaile Li, Fang-Lin Sun, Jianfeng Chang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cell Communication and Signaling
Subjects:
NASP
Androgen receptor
Prostate cancer
EMT
Histone turnover
Epigenetic landscape
Online Access:https://doi.org/10.1186/s12964-025-02339-0
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