Gene therapy in the putamen for curing AADC deficiency and Parkinson's disease
Abstract This commentary provides an overview of the putamen as an established target site for gene therapy in treating aromatic l‐amino acid decarboxylase (AADC) deficiency and Parkinson’s disease, two debilitating neurological disorders that involve motor dysfunction caused by dopamine deficiencie...
Saved in:
| Main Authors: | Paul Wuh‐Liang Hwu, Karl Kiening, Irina Anselm, David R Compton, Takeshi Nakajima, Thomas Opladen, Phillip L Pearl, Agathe Roubertie, Thomas Roujeau, Shin‐ichi Muramatsu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2021-08-01
|
| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.202114712 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Patient selection considerations for AADC deficiency gene therapy
by: Agathe Roubertie, et al.
Published: (2024-03-01) -
In silico analysis of hub genes and regulatory networks implicates the putamen in non-motor Parkinson’s disease disorders
by: Stephen Tunmise Akanbi, et al.
Published: (2025-01-01) -
Aromatic L-amino acid decarboxylase deficiency – disease under the masks of cerebral palsy and epilepsy
by: N. V. Chebanenko
Published: (2024-05-01) -
Incorporating “kawaii-ness” into your life may increase gray matter volume in the putamen and frontal gyrus
by: Keisuke Kokubun, et al.
Published: (2025-02-01) -
PENGARUH PEMBERIAN RANITIDIN TERHADAP GAMBARAN HISTOPATOLOGI PUTAMEN TIKUS WISTAR PADA PEMBERIAN METANOL DOSIS BERTINGKAT
by: Tan Nadia Paramitha Purnama, et al.
Published: (2017-06-01)