Evaluation of Osteoporosis in Hemophilic Arthropathy Patients: Correlation with Disease Severity and Serum Trace Minerals
Objective. To find out the presence of osteoporosis in hemophilic arthropathy patients and its correlation with clinical severity and serum levels of magnesium, copper, and zinc. Methods. Joint score, functional assessment score, bone densitometry, and serum magnesium, copper and zinc were done in t...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Journal of Osteoporosis |
| Online Access: | http://dx.doi.org/10.4061/2011/106380 |
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| author | Eiman Mahmoud Ghaniema Sahar Fathi Ahmed Irene Raouf Amin Maryse Soliman Ayoub |
| author_facet | Eiman Mahmoud Ghaniema Sahar Fathi Ahmed Irene Raouf Amin Maryse Soliman Ayoub |
| author_sort | Eiman Mahmoud Ghaniema |
| collection | DOAJ |
| description | Objective. To find out the presence of osteoporosis in hemophilic arthropathy patients and its correlation with clinical severity and serum levels of magnesium, copper, and zinc. Methods. Joint score, functional assessment score, bone densitometry, and serum magnesium, copper and zinc were done in twenty male hemophilic arthropathy patients and twenty controls. Results. There was highly significant lower Z scores of lumbar spine and neck of femur in patients versus controls (P<0.011). Z score of neck of femur correlated negatively with total joint score (P=0.013) and functional assessment score (P=0.011). Serum levels of copper and zinc correlated positively with Z score of neck of femur (P=0.004, P=0.001, resp.). Conclusion. Osteoporosis represents a frequent concomitant observation in hemophiliacs. Screening of young hemophiliacs for osteoporosis is recommended with measuring serum levels of magnesium, copper, and zinc for better management of the disease. |
| format | Article |
| id | doaj-art-fb61771f460242518a683edbe51040f6 |
| institution | OA Journals |
| issn | 2042-0064 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Osteoporosis |
| spelling | doaj-art-fb61771f460242518a683edbe51040f62025-08-20T02:22:55ZengWileyJournal of Osteoporosis2042-00642011-01-01201110.4061/2011/106380106380Evaluation of Osteoporosis in Hemophilic Arthropathy Patients: Correlation with Disease Severity and Serum Trace MineralsEiman Mahmoud Ghaniema0Sahar Fathi Ahmed1Irene Raouf Amin2Maryse Soliman Ayoub3Rheumatology and Rehabilitation Department, Ain Shams University, Cairo 11566, EgyptRheumatology and Rehabilitation Department, Ain Shams University, Cairo 11566, EgyptRheumatology and Rehabilitation Department, Ain Shams University, Cairo 11566, EgyptInternal Medicine Department (Hematology Unit), Ain Shams University, Cairo 11566, EgyptObjective. To find out the presence of osteoporosis in hemophilic arthropathy patients and its correlation with clinical severity and serum levels of magnesium, copper, and zinc. Methods. Joint score, functional assessment score, bone densitometry, and serum magnesium, copper and zinc were done in twenty male hemophilic arthropathy patients and twenty controls. Results. There was highly significant lower Z scores of lumbar spine and neck of femur in patients versus controls (P<0.011). Z score of neck of femur correlated negatively with total joint score (P=0.013) and functional assessment score (P=0.011). Serum levels of copper and zinc correlated positively with Z score of neck of femur (P=0.004, P=0.001, resp.). Conclusion. Osteoporosis represents a frequent concomitant observation in hemophiliacs. Screening of young hemophiliacs for osteoporosis is recommended with measuring serum levels of magnesium, copper, and zinc for better management of the disease.http://dx.doi.org/10.4061/2011/106380 |
| spellingShingle | Eiman Mahmoud Ghaniema Sahar Fathi Ahmed Irene Raouf Amin Maryse Soliman Ayoub Evaluation of Osteoporosis in Hemophilic Arthropathy Patients: Correlation with Disease Severity and Serum Trace Minerals Journal of Osteoporosis |
| title | Evaluation of Osteoporosis in Hemophilic Arthropathy Patients: Correlation with Disease Severity and Serum Trace Minerals |
| title_full | Evaluation of Osteoporosis in Hemophilic Arthropathy Patients: Correlation with Disease Severity and Serum Trace Minerals |
| title_fullStr | Evaluation of Osteoporosis in Hemophilic Arthropathy Patients: Correlation with Disease Severity and Serum Trace Minerals |
| title_full_unstemmed | Evaluation of Osteoporosis in Hemophilic Arthropathy Patients: Correlation with Disease Severity and Serum Trace Minerals |
| title_short | Evaluation of Osteoporosis in Hemophilic Arthropathy Patients: Correlation with Disease Severity and Serum Trace Minerals |
| title_sort | evaluation of osteoporosis in hemophilic arthropathy patients correlation with disease severity and serum trace minerals |
| url | http://dx.doi.org/10.4061/2011/106380 |
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