Medication-Related Burden among Iraqi Patients with Crohn’s Disease: A Cross Sectional Study
Crohn’s disease is an inflammatory bowel disease that is characterized by chronic inflammation of any part of the gastrointestinal tract, has a progressive and destructive course and is increasing in incidence worldwide. Medical treatment of Crohn’s disease is usually divided into remission inducti...
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College of Pharmacy University of Baghdad
2024-12-01
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| Series: | Iraqi Journal of Pharmaceutical Sciences |
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| Online Access: | https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/2861 |
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| author | Nawar Abdulridha Abood Dheyaa J. Kadhim Raghad Jawad Hussein |
| author_facet | Nawar Abdulridha Abood Dheyaa J. Kadhim Raghad Jawad Hussein |
| author_sort | Nawar Abdulridha Abood |
| collection | DOAJ |
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Crohn’s disease is an inflammatory bowel disease that is characterized by chronic inflammation of any part of the gastrointestinal tract, has a progressive and destructive course and is increasing in incidence worldwide. Medical treatment of Crohn’s disease is usually divided into remission induction therapy and remission maintenance therapy. Medication-related burden is a new concept focused on the negative experiences resulting from taking medicines. The aims of the current study were to measure medication-related burden among a sample of Iraqi patients with Crohn’s disease, and to determine any associations between medication-related burden and some patient factors. The present study was cross-sectional conducted at ‟Gastroenterology and Hepatology Teaching Hospital/ Medical City / Baghdad / Iraq” during December 2022 to May 2023. The Arabic version of living with medicine questionnaire was used to measure medication-related burden experienced by the patients. 94 Crohn’s disease were included [Males =58 (61.7%), Females=36 (38.3%)] with mean age (31.9±10.8 years). The mean of total burden score was (102.7 ± 20.6) with more than half (54.3%) of the patients experienced a minimum degree of medication burden, followed by moderate burden (29.8%), no burden (8.5%) and high burden (7.4%). Three domains showed the highest mean of burden scores: “Cost Related Burden”, “concerns about medicines use” and “Autonomy to vary regimen”. Total burden score, “side effects of medicines” and “effectiveness of prescribed medications” domains were significantly lower in remission patients compared to active cases. In conclusion, a large proportion of the Crohn’s disease have experienced varying degrees of medication-related burden. Disease activity was independently correlated with total burden score.
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| format | Article |
| id | doaj-art-fb4893f6b4bb4161bc52d76980f07f4f |
| institution | OA Journals |
| issn | 1683-3597 2521-3512 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | College of Pharmacy University of Baghdad |
| record_format | Article |
| series | Iraqi Journal of Pharmaceutical Sciences |
| spelling | doaj-art-fb4893f6b4bb4161bc52d76980f07f4f2025-08-20T02:34:50ZengCollege of Pharmacy University of BaghdadIraqi Journal of Pharmaceutical Sciences1683-35972521-35122024-12-0133410.31351/vol33iss4pp89-95Medication-Related Burden among Iraqi Patients with Crohn’s Disease: A Cross Sectional StudyNawar Abdulridha Abood0Dheyaa J. Kadhim 1Raghad Jawad Hussein2M.Sc. Student, College of Pharmacy, University of Baghdad, Baghdad, IraqDepartment of Clinical Pharmacy, College of Pharmacy, University of Baghdad, Baghdad, IraqMinistry of Health, The Gastroenterology and Hepatology Teaching Hospital, Medical City, Baghdad, Iraq. Crohn’s disease is an inflammatory bowel disease that is characterized by chronic inflammation of any part of the gastrointestinal tract, has a progressive and destructive course and is increasing in incidence worldwide. Medical treatment of Crohn’s disease is usually divided into remission induction therapy and remission maintenance therapy. Medication-related burden is a new concept focused on the negative experiences resulting from taking medicines. The aims of the current study were to measure medication-related burden among a sample of Iraqi patients with Crohn’s disease, and to determine any associations between medication-related burden and some patient factors. The present study was cross-sectional conducted at ‟Gastroenterology and Hepatology Teaching Hospital/ Medical City / Baghdad / Iraq” during December 2022 to May 2023. The Arabic version of living with medicine questionnaire was used to measure medication-related burden experienced by the patients. 94 Crohn’s disease were included [Males =58 (61.7%), Females=36 (38.3%)] with mean age (31.9±10.8 years). The mean of total burden score was (102.7 ± 20.6) with more than half (54.3%) of the patients experienced a minimum degree of medication burden, followed by moderate burden (29.8%), no burden (8.5%) and high burden (7.4%). Three domains showed the highest mean of burden scores: “Cost Related Burden”, “concerns about medicines use” and “Autonomy to vary regimen”. Total burden score, “side effects of medicines” and “effectiveness of prescribed medications” domains were significantly lower in remission patients compared to active cases. In conclusion, a large proportion of the Crohn’s disease have experienced varying degrees of medication-related burden. Disease activity was independently correlated with total burden score. https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/2861Medication-Related BurdenIraqCrohn’s Diseaseinflammatory bowel diseaseliving with medicine questionnaire |
| spellingShingle | Nawar Abdulridha Abood Dheyaa J. Kadhim Raghad Jawad Hussein Medication-Related Burden among Iraqi Patients with Crohn’s Disease: A Cross Sectional Study Iraqi Journal of Pharmaceutical Sciences Medication-Related Burden Iraq Crohn’s Disease inflammatory bowel disease living with medicine questionnaire |
| title | Medication-Related Burden among Iraqi Patients with Crohn’s Disease: A Cross Sectional Study |
| title_full | Medication-Related Burden among Iraqi Patients with Crohn’s Disease: A Cross Sectional Study |
| title_fullStr | Medication-Related Burden among Iraqi Patients with Crohn’s Disease: A Cross Sectional Study |
| title_full_unstemmed | Medication-Related Burden among Iraqi Patients with Crohn’s Disease: A Cross Sectional Study |
| title_short | Medication-Related Burden among Iraqi Patients with Crohn’s Disease: A Cross Sectional Study |
| title_sort | medication related burden among iraqi patients with crohn s disease a cross sectional study |
| topic | Medication-Related Burden Iraq Crohn’s Disease inflammatory bowel disease living with medicine questionnaire |
| url | https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/2861 |
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