Fatal Dermal Absorption of Organophosphate Insecticide

Organophosphate compounds are one of the leading causes of death due to poisoning worldwide due to their easy accessibility as insectides and pesticides. Ninety-five percent of pesticide poisonings occur in developing countries, especially in the Asia–Pacific region. Moreover, in countries like Indi...

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Main Authors: Shankar M Bakkannavar, Vinod C Nayak
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Proceedings
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Online Access:https://www.mdpi.com/2504-3900/102/1/43
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author Shankar M Bakkannavar
Vinod C Nayak
author_facet Shankar M Bakkannavar
Vinod C Nayak
author_sort Shankar M Bakkannavar
collection DOAJ
description Organophosphate compounds are one of the leading causes of death due to poisoning worldwide due to their easy accessibility as insectides and pesticides. Ninety-five percent of pesticide poisonings occur in developing countries, especially in the Asia–Pacific region. Moreover, in countries like India, pesticides are one of the most commonly used suicidal poisons because of their easy accessibility. Agriculture being the country's main source of occupation, pesticides are easily accessible throughout India. Organophosphorus toxicity can commonly occur due to household pesticide use or due to occupational exposure. Though rare, accidental poisoning can occur in people working in the pesticide industry, farmers, and sometimes in the general population. Organophosphorus compounds are absorbed by all routes and cause fatality unless treated with the appropriate antidote. Suicidal poisoning will usually be by ingestion, whereas accidental poisoning will be either inhalational or dermal. Homicidal poisoning cases with the use of organophosphorus compounds have also been reported in the literature. People may become unknowing victims of these chemicals. The dermal absorption of these compounds is common, but it rarely results in fatality. Acute poisoning is common after oral, respiratory, or dermal exposure to low-volatility or high-volatility pesticides. We present an accidental fatal case of organophosphorus poisoning wherein the mode of entry was through dermal absorption.
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spelling doaj-art-fb421ad4723744ca8f1f0ba0a4836eac2025-08-20T03:29:40ZengMDPI AGProceedings2504-39002024-04-0110214310.3390/proceedings2024102043Fatal Dermal Absorption of Organophosphate InsecticideShankar M Bakkannavar0Vinod C Nayak1Kasturba Medical College, Manipal Academy of Higher Education, Manipal 576104, IndiaKasturba Medical College, Manipal Academy of Higher Education, Manipal 576104, IndiaOrganophosphate compounds are one of the leading causes of death due to poisoning worldwide due to their easy accessibility as insectides and pesticides. Ninety-five percent of pesticide poisonings occur in developing countries, especially in the Asia–Pacific region. Moreover, in countries like India, pesticides are one of the most commonly used suicidal poisons because of their easy accessibility. Agriculture being the country's main source of occupation, pesticides are easily accessible throughout India. Organophosphorus toxicity can commonly occur due to household pesticide use or due to occupational exposure. Though rare, accidental poisoning can occur in people working in the pesticide industry, farmers, and sometimes in the general population. Organophosphorus compounds are absorbed by all routes and cause fatality unless treated with the appropriate antidote. Suicidal poisoning will usually be by ingestion, whereas accidental poisoning will be either inhalational or dermal. Homicidal poisoning cases with the use of organophosphorus compounds have also been reported in the literature. People may become unknowing victims of these chemicals. The dermal absorption of these compounds is common, but it rarely results in fatality. Acute poisoning is common after oral, respiratory, or dermal exposure to low-volatility or high-volatility pesticides. We present an accidental fatal case of organophosphorus poisoning wherein the mode of entry was through dermal absorption.https://www.mdpi.com/2504-3900/102/1/43organophosphate compoundspesticide poisoningdermal absorption
spellingShingle Shankar M Bakkannavar
Vinod C Nayak
Fatal Dermal Absorption of Organophosphate Insecticide
Proceedings
organophosphate compounds
pesticide poisoning
dermal absorption
title Fatal Dermal Absorption of Organophosphate Insecticide
title_full Fatal Dermal Absorption of Organophosphate Insecticide
title_fullStr Fatal Dermal Absorption of Organophosphate Insecticide
title_full_unstemmed Fatal Dermal Absorption of Organophosphate Insecticide
title_short Fatal Dermal Absorption of Organophosphate Insecticide
title_sort fatal dermal absorption of organophosphate insecticide
topic organophosphate compounds
pesticide poisoning
dermal absorption
url https://www.mdpi.com/2504-3900/102/1/43
work_keys_str_mv AT shankarmbakkannavar fataldermalabsorptionoforganophosphateinsecticide
AT vinodcnayak fataldermalabsorptionoforganophosphateinsecticide