Influenza a virus assembly intermediates fuse in the cytoplasm.

Influenza a virus assembly intermediates fuse in the cytoplasm.

Reassortment of influenza viral RNA (vRNA) segments in co-infected cells can lead to the emergence of viruses with pandemic potential. Replication of influenza vRNA occurs in the nucleus of infected cells, while progeny virions bud from the plasma membrane. However, the intracellular mechanics of vR...

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Bibliographic Details
Main Authors: Seema S Lakdawala, Yicong Wu, Peter Wawrzusin, Juraj Kabat, Andrew J Broadbent, Elaine W Lamirande, Ervin Fodor, Nihal Altan-Bonnet, Hari Shroff, Kanta Subbarao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1003971
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