Dysregulated neurofluid coupling as a new noninvasive biomarker for primary progressive aphasia

Dysregulated neurofluid coupling as a new noninvasive biomarker for primary progressive aphasia

Accumulation of pathological tau is one of the primary causes of Primary Progressive Aphasia (PPA). The glymphatic system is crucial for removing metabolite waste from the brain whereas impairments in glymphatic clearance in PPA are poorly understood. Thus, this study aims to investigate the role of...

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Bibliographic Details
Main Authors: Xinglin Zeng, Lin Hua, Guolin Ma, Zhiying Zhao, Zhen Yuan
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:NeuroImage
Subjects:
Primary progressive aphasia
Frontotemporal dementia
Cerebrospinal fluid
Glymphatic function
Global brain activity
Online Access:http://www.sciencedirect.com/science/article/pii/S105381192400421X
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