Salivary Statherin as a Dental Caries Biomarker among a Sample of Adolescents in Baghdad City
Background: Dental caries represents a multifaceted disease impacting teenagers across the globe. A combination of factors, including fermentable carbohydrates, acid-producing bacteria, saliva, and host-related characteristics, influences its development. Salivary statherin controls microorganisms...
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University of Baghdad/ Al-Kindy College of Medicine
2024-12-01
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| Series: | مجله كليه طب الكندي |
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| Online Access: | https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/971 |
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| author | Sara Hikmat Yousif Alhan Ahmed Qasim |
| author_facet | Sara Hikmat Yousif Alhan Ahmed Qasim |
| author_sort | Sara Hikmat Yousif |
| collection | DOAJ |
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Background: Dental caries represents a multifaceted disease impacting teenagers across the globe. A combination of factors, including fermentable carbohydrates, acid-producing bacteria, saliva, and host-related characteristics, influences its development. Salivary statherin controls microorganisms by aggregating them and preventing them from adhering to hard tissue and epithelium. Salivary statherin may maintain tooth integrity.
Objective: This research investigated the potential of salivary statherin as a biomarker for dental caries, examining its connection to the nutritional status of adolescents.
Subjects and Methods: This comparative (observational) research included 90 15-year-old adolescents of both sexes. Participants were divided into two distinct groups: 30 individuals without caries, serving as the control group, and 60 individuals with caries, referred to as the study group. Following the World Health Organization guidelines, adolescents with varying caries experiences were further categorized. Thirty of them exhibited a moderate level of caries, with 1 to 3 affected teeth, while the remaining thirty were classified as having severe caries, with a Decay-Missing-Filled Teeth (DMFT) score greater than 10. The DMFT Index measured caries experience. Salivary statherin analysis from unstimulated saliva. Height, weight, and body mass index measured nutrition, classifying adolescents as normal weight, overweight, or obese.
Results: Statherin levels decreased with the severity of caries increasing. There was a significant result in the overweight, healthy, and total sample among caries severity groups (P value <= 0.05). There was a significant difference in the severe caries group, while statherin levels increased with nutritional status (P value ≤ 0.05).
Conclusions: Caries severity reduces salivary statherin. In severe caries patients, nutritional status increased salivary statherin. Dietary status and dental caries severity affected statherin levels. No association was found between statherin levels and salivary pH or flow rate across different nutritional statuses or caries severity groups. However, salivary statherin may play a role in maintaining tooth integrity
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| format | Article |
| id | doaj-art-fb3ac2c6e4ac456f92a7d3faac9fb5d9 |
| institution | OA Journals |
| issn | 1810-9543 2521-4365 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | University of Baghdad/ Al-Kindy College of Medicine |
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| series | مجله كليه طب الكندي |
| spelling | doaj-art-fb3ac2c6e4ac456f92a7d3faac9fb5d92025-08-20T02:19:27ZengUniversity of Baghdad/ Al-Kindy College of Medicineمجله كليه طب الكندي1810-95432521-43652024-12-0120310.47723/3dx8ez73897Salivary Statherin as a Dental Caries Biomarker among a Sample of Adolescents in Baghdad CitySara Hikmat Yousif0https://orcid.org/0000-0002-4507-1406Alhan Ahmed Qasim1https://orcid.org/0000-0003-0682-664XDepartment of Pediatric and Preventive Dentistry, College of Dentistry, University of Baghdad, Baghdad, IraqDepartment of Pediatric and Preventive Dentistry, College of Dentistry, University of Baghdad, Baghdad, Iraq Background: Dental caries represents a multifaceted disease impacting teenagers across the globe. A combination of factors, including fermentable carbohydrates, acid-producing bacteria, saliva, and host-related characteristics, influences its development. Salivary statherin controls microorganisms by aggregating them and preventing them from adhering to hard tissue and epithelium. Salivary statherin may maintain tooth integrity. Objective: This research investigated the potential of salivary statherin as a biomarker for dental caries, examining its connection to the nutritional status of adolescents. Subjects and Methods: This comparative (observational) research included 90 15-year-old adolescents of both sexes. Participants were divided into two distinct groups: 30 individuals without caries, serving as the control group, and 60 individuals with caries, referred to as the study group. Following the World Health Organization guidelines, adolescents with varying caries experiences were further categorized. Thirty of them exhibited a moderate level of caries, with 1 to 3 affected teeth, while the remaining thirty were classified as having severe caries, with a Decay-Missing-Filled Teeth (DMFT) score greater than 10. The DMFT Index measured caries experience. Salivary statherin analysis from unstimulated saliva. Height, weight, and body mass index measured nutrition, classifying adolescents as normal weight, overweight, or obese. Results: Statherin levels decreased with the severity of caries increasing. There was a significant result in the overweight, healthy, and total sample among caries severity groups (P value <= 0.05). There was a significant difference in the severe caries group, while statherin levels increased with nutritional status (P value ≤ 0.05). Conclusions: Caries severity reduces salivary statherin. In severe caries patients, nutritional status increased salivary statherin. Dietary status and dental caries severity affected statherin levels. No association was found between statherin levels and salivary pH or flow rate across different nutritional statuses or caries severity groups. However, salivary statherin may play a role in maintaining tooth integrity https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/971AdolescentsDental CariesNutrition StatusSalivary Statherian |
| spellingShingle | Sara Hikmat Yousif Alhan Ahmed Qasim Salivary Statherin as a Dental Caries Biomarker among a Sample of Adolescents in Baghdad City مجله كليه طب الكندي Adolescents Dental Caries Nutrition Status Salivary Statherian |
| title | Salivary Statherin as a Dental Caries Biomarker among a Sample of Adolescents in Baghdad City |
| title_full | Salivary Statherin as a Dental Caries Biomarker among a Sample of Adolescents in Baghdad City |
| title_fullStr | Salivary Statherin as a Dental Caries Biomarker among a Sample of Adolescents in Baghdad City |
| title_full_unstemmed | Salivary Statherin as a Dental Caries Biomarker among a Sample of Adolescents in Baghdad City |
| title_short | Salivary Statherin as a Dental Caries Biomarker among a Sample of Adolescents in Baghdad City |
| title_sort | salivary statherin as a dental caries biomarker among a sample of adolescents in baghdad city |
| topic | Adolescents Dental Caries Nutrition Status Salivary Statherian |
| url | https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/971 |
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