Efficacy of unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) in China: protocol for a randomised controlled trial
Introduction Emotional disorders are highly prevalent among adolescents, with a high rate of comorbidity. Convenient and effective treatment options are needed to reduce costs and improve effectiveness. The unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) i...
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BMJ Publishing Group
2025-02-01
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| Series: | BMJ Open |
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| author | Xue Gao Lu Liu Mei-Rong Pan Hai-Mei Li Yu-Feng Wang Xue-Ying Liu Zhong-Fang Fu Qiujin Qian |
| author_facet | Xue Gao Lu Liu Mei-Rong Pan Hai-Mei Li Yu-Feng Wang Xue-Ying Liu Zhong-Fang Fu Qiujin Qian |
| author_sort | Xue Gao |
| collection | DOAJ |
| description | Introduction Emotional disorders are highly prevalent among adolescents, with a high rate of comorbidity. Convenient and effective treatment options are needed to reduce costs and improve effectiveness. The unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) is an evidence-based transdiagnostic approach aimed at ameliorate emotional symptoms. The objective of this study is to assess the efficacy of the UP-A in Chinese adolescents with emotional disorders using multidimensional evaluations.Methods and analysis This study is a two-armed, randomised controlled trial on the efficacy of 12 week UP-A on adolescents with emotional disorders along with their parents. Forty-eight participants will be randomly assigned to either the treatment as usual (TAU) group or the TAU combined with UP-A (UP-A+TAU) group. We will evaluate the efficacy of the UP-A, through the following primary and secondary outcomes: emotional disorder severity, emotional symptoms, emotion regulation, cognitive patterns, executive function, resilience, quality of life, social and family functioning. Participants will be assessed at baseline (T1), week 4 (T2), week 8 (T3), post-treatment (T4) and 3 month follow-up (T5).Discussion This protocol outlines the first randomised controlled trial investigating the efficacy of the UP-A among Chinese adolescents with emotional disorders. The findings may contribute to providing an effective and feasible transdiagnostic intervention in Chinese clinical settings.Ethics and dissemination This trial has been approved by the Ethics and Clinical Research Committees of Peking University Sixth Hospital and will be performed under the Declaration of Helsinki with the Medical Research Involving Human Subjects Act (WMO). The results will be disseminated in a peer-reviewed journal and a conference presentation.Trial registration number ChiCTR2300069354. |
| format | Article |
| id | doaj-art-fb3a8dbe50aa4d7db0d1c47ed4ce90d2 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-fb3a8dbe50aa4d7db0d1c47ed4ce90d22025-02-11T08:25:08ZengBMJ Publishing GroupBMJ Open2044-60552025-02-0115210.1136/bmjopen-2024-091352Efficacy of unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) in China: protocol for a randomised controlled trialXue Gao0Lu Liu1Mei-Rong Pan2Hai-Mei Li3Yu-Feng Wang4Xue-Ying Liu5Zhong-Fang Fu6Qiujin Qian7National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Peking University NHC Key Laboratory of Mental Health, Beijing, ChinaInstitute of Mental Health, Peking University Sixth Hospital, Beijing, ChinaInstitute of Mental Health, Peking University Sixth Hospital, Beijing, ChinaNational Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Peking University NHC Key Laboratory of Mental Health, Beijing, ChinaInstitute of Mental Health, Peking University Sixth Hospital, Beijing, ChinaInstitute of Mental Health, Peking University Sixth Hospital, Beijing, ChinaBeijing Key Laboratory of Behavior and Mental Health, Peking University School of Psychological and Cognitive Sciences, Beijing, ChinaInstitute of Mental Health, Peking University Sixth Hospital, Beijing, ChinaIntroduction Emotional disorders are highly prevalent among adolescents, with a high rate of comorbidity. Convenient and effective treatment options are needed to reduce costs and improve effectiveness. The unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) is an evidence-based transdiagnostic approach aimed at ameliorate emotional symptoms. The objective of this study is to assess the efficacy of the UP-A in Chinese adolescents with emotional disorders using multidimensional evaluations.Methods and analysis This study is a two-armed, randomised controlled trial on the efficacy of 12 week UP-A on adolescents with emotional disorders along with their parents. Forty-eight participants will be randomly assigned to either the treatment as usual (TAU) group or the TAU combined with UP-A (UP-A+TAU) group. We will evaluate the efficacy of the UP-A, through the following primary and secondary outcomes: emotional disorder severity, emotional symptoms, emotion regulation, cognitive patterns, executive function, resilience, quality of life, social and family functioning. Participants will be assessed at baseline (T1), week 4 (T2), week 8 (T3), post-treatment (T4) and 3 month follow-up (T5).Discussion This protocol outlines the first randomised controlled trial investigating the efficacy of the UP-A among Chinese adolescents with emotional disorders. The findings may contribute to providing an effective and feasible transdiagnostic intervention in Chinese clinical settings.Ethics and dissemination This trial has been approved by the Ethics and Clinical Research Committees of Peking University Sixth Hospital and will be performed under the Declaration of Helsinki with the Medical Research Involving Human Subjects Act (WMO). The results will be disseminated in a peer-reviewed journal and a conference presentation.Trial registration number ChiCTR2300069354.https://bmjopen.bmj.com/content/15/2/e091352.full |
| spellingShingle | Xue Gao Lu Liu Mei-Rong Pan Hai-Mei Li Yu-Feng Wang Xue-Ying Liu Zhong-Fang Fu Qiujin Qian Efficacy of unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) in China: protocol for a randomised controlled trial BMJ Open |
| title | Efficacy of unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) in China: protocol for a randomised controlled trial |
| title_full | Efficacy of unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) in China: protocol for a randomised controlled trial |
| title_fullStr | Efficacy of unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) in China: protocol for a randomised controlled trial |
| title_full_unstemmed | Efficacy of unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) in China: protocol for a randomised controlled trial |
| title_short | Efficacy of unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) in China: protocol for a randomised controlled trial |
| title_sort | efficacy of unified protocol for transdiagnostic treatment of emotional disorders in adolescents up a in china protocol for a randomised controlled trial |
| url | https://bmjopen.bmj.com/content/15/2/e091352.full |
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