Loss of cofilin 1 disturbs actin dynamics, adhesion between enveloping and deep cell layers and cell movements during gastrulation in zebrafish.

During gastrulation, cohesive migration drives associated cell layers to the completion of epiboly in zebrafish. The association of different layers relies on E-cadherin based cellular junctions, whose stability can be affected by actin turnover. Here, we examined the effect of malfunctioning actin...

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Main Authors: Chun-Wei Lin, Shuo-Ting Yen, Hui-Ting Chang, Shiang-Jiuun Chen, Shih-Lei Lai, Yi-Ching Liu, Tun-Hao Chan, Wen-Lian Liao, Shyh-Jye Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0015331&type=printable
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