Machine learning approach for studying the neural underpinnings of dyslexia on a phonological awareness task

Understanding the neural underpinnings of dyslexia is an open and fundamental question in developmental neuroscience. A widely agreed causal risk factor for dyslexia is phonological deficit (PD). However, the causal relationships between PD and dyslexia have been primarily investigated and theorized...

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Main Authors: Christoforos Christoforou, Timothy C. Papadopoulos, Maria Theodorou
Format: Article
Language:English
Published: LibraryPress@UF 2022-05-01
Series:Proceedings of the International Florida Artificial Intelligence Research Society Conference
Subjects:
Online Access:https://journals.flvc.org/FLAIRS/article/view/130576
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author Christoforos Christoforou
Timothy C. Papadopoulos
Maria Theodorou
author_facet Christoforos Christoforou
Timothy C. Papadopoulos
Maria Theodorou
author_sort Christoforos Christoforou
collection DOAJ
description Understanding the neural underpinnings of dyslexia is an open and fundamental question in developmental neuroscience. A widely agreed causal risk factor for dyslexia is phonological deficit (PD). However, the causal relationships between PD and dyslexia have been primarily investigated and theorized based on findings derived from behavioral measures. What is missing is evidence of the underlying neurophysiological origins of these relationships. The present study examined whether the performance on a phonological awareness task, namely phoneme elision (PE), differentiated children with dyslexia from their typically developing counterparts at a neural level. We proposed a novel machine-learning-based approach to extract neural activity from EEG to identify neural differences at the group level. Specifically, we formulated an optimization problem to first extract informative EEG components (termed phoneme-related neural-congruency components) by maximizing the congruency in neural activity among typically developing children during phoneme elision. Next, we utilized a machine-learning algorithm to optimally combine the resulting components to differentiate between children with dyslexia and controls. Results showed that the proposed phoneme-related neural-congruency components are predictive about the underlying neuronal differences amongst groups. These results provide empirical evidence towards the neural underpinnings of dyslexia and the potential neural origins of PD as a causal link to dyslexia. Notably, the proposed method could be used to study other behaviorally defined developmental disorders.
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spelling doaj-art-fb34384705b34bcd93db2bab54aecaf22025-08-20T03:07:32ZengLibraryPress@UFProceedings of the International Florida Artificial Intelligence Research Society Conference2334-07542334-07622022-05-013510.32473/flairs.v35i.13057666775Machine learning approach for studying the neural underpinnings of dyslexia on a phonological awareness taskChristoforos Christoforou0Timothy C. Papadopoulos1Maria TheodorouSt. John's UniversityDepartment of Psychology & Center for Applied Neuroscience, University of CyprusUnderstanding the neural underpinnings of dyslexia is an open and fundamental question in developmental neuroscience. A widely agreed causal risk factor for dyslexia is phonological deficit (PD). However, the causal relationships between PD and dyslexia have been primarily investigated and theorized based on findings derived from behavioral measures. What is missing is evidence of the underlying neurophysiological origins of these relationships. The present study examined whether the performance on a phonological awareness task, namely phoneme elision (PE), differentiated children with dyslexia from their typically developing counterparts at a neural level. We proposed a novel machine-learning-based approach to extract neural activity from EEG to identify neural differences at the group level. Specifically, we formulated an optimization problem to first extract informative EEG components (termed phoneme-related neural-congruency components) by maximizing the congruency in neural activity among typically developing children during phoneme elision. Next, we utilized a machine-learning algorithm to optimally combine the resulting components to differentiate between children with dyslexia and controls. Results showed that the proposed phoneme-related neural-congruency components are predictive about the underlying neuronal differences amongst groups. These results provide empirical evidence towards the neural underpinnings of dyslexia and the potential neural origins of PD as a causal link to dyslexia. Notably, the proposed method could be used to study other behaviorally defined developmental disorders.https://journals.flvc.org/FLAIRS/article/view/130576eegneural-congruencyfirst phoneme elisiondyslexiamachine learningelectroencephalography
spellingShingle Christoforos Christoforou
Timothy C. Papadopoulos
Maria Theodorou
Machine learning approach for studying the neural underpinnings of dyslexia on a phonological awareness task
Proceedings of the International Florida Artificial Intelligence Research Society Conference
eeg
neural-congruency
first phoneme elision
dyslexia
machine learning
electroencephalography
title Machine learning approach for studying the neural underpinnings of dyslexia on a phonological awareness task
title_full Machine learning approach for studying the neural underpinnings of dyslexia on a phonological awareness task
title_fullStr Machine learning approach for studying the neural underpinnings of dyslexia on a phonological awareness task
title_full_unstemmed Machine learning approach for studying the neural underpinnings of dyslexia on a phonological awareness task
title_short Machine learning approach for studying the neural underpinnings of dyslexia on a phonological awareness task
title_sort machine learning approach for studying the neural underpinnings of dyslexia on a phonological awareness task
topic eeg
neural-congruency
first phoneme elision
dyslexia
machine learning
electroencephalography
url https://journals.flvc.org/FLAIRS/article/view/130576
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