A Simple and Convenient Method for Simultaneous Determination of Schizandrol A, Schizandrol B, Schisandrin A, γ-Schisandrin, and Schisandrin C
A simple, rapid, and specific HPLC method was established for simultaneous determination of five major lignans (Schizandrol A, Schizandrol B, Schisandrin A, γ-Schisandrin, and Schisandrin C) in Schisandra chinensis. The five lignans can be separated completely on Kromasil C18 column (250 nm × 4.6 nm...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
|
| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2016/1739879 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832549135876620288 |
|---|---|
| author | Yu Zhou Wu Ling Wei Jiang Xing Hua Qingsheng Fan |
| author_facet | Yu Zhou Wu Ling Wei Jiang Xing Hua Qingsheng Fan |
| author_sort | Yu Zhou |
| collection | DOAJ |
| description | A simple, rapid, and specific HPLC method was established for simultaneous determination of five major lignans (Schizandrol A, Schizandrol B, Schisandrin A, γ-Schisandrin, and Schisandrin C) in Schisandra chinensis. The five lignans can be separated completely on Kromasil C18 column (250 nm × 4.6 nm) and then detected at 254 nm using methanol (mobile phase A) and water (mobile phase B) with gradient elution as the mobile phase at 1.0 mL/min flow rate. The column temperature was 30°C. The method was validated in terms of linearity, precision, stability, repeatability, and recovery. Results showed that the method is accurate and reproducible. |
| format | Article |
| id | doaj-art-fb31c6cdb2374bec8c06175718d877f7 |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-fb31c6cdb2374bec8c06175718d877f72025-02-03T06:12:13ZengWileyJournal of Chemistry2090-90632090-90712016-01-01201610.1155/2016/17398791739879A Simple and Convenient Method for Simultaneous Determination of Schizandrol A, Schizandrol B, Schisandrin A, γ-Schisandrin, and Schisandrin CYu Zhou0Wu Ling Wei1Jiang Xing Hua2Qingsheng Fan3Sino-German Joint Research Institution, Nanchang University, 235 Nanjing East Road, Nanchang 330047, ChinaSino-German Joint Research Institution, Nanchang University, 235 Nanjing East Road, Nanchang 330047, ChinaBureau of Agriculture and Grain of Ganzhou, Changzheng Road, The Municipal Building, Zhanggong District, Ganzhou 341000, ChinaSino-German Joint Research Institution, Nanchang University, 235 Nanjing East Road, Nanchang 330047, ChinaA simple, rapid, and specific HPLC method was established for simultaneous determination of five major lignans (Schizandrol A, Schizandrol B, Schisandrin A, γ-Schisandrin, and Schisandrin C) in Schisandra chinensis. The five lignans can be separated completely on Kromasil C18 column (250 nm × 4.6 nm) and then detected at 254 nm using methanol (mobile phase A) and water (mobile phase B) with gradient elution as the mobile phase at 1.0 mL/min flow rate. The column temperature was 30°C. The method was validated in terms of linearity, precision, stability, repeatability, and recovery. Results showed that the method is accurate and reproducible.http://dx.doi.org/10.1155/2016/1739879 |
| spellingShingle | Yu Zhou Wu Ling Wei Jiang Xing Hua Qingsheng Fan A Simple and Convenient Method for Simultaneous Determination of Schizandrol A, Schizandrol B, Schisandrin A, γ-Schisandrin, and Schisandrin C Journal of Chemistry |
| title | A Simple and Convenient Method for Simultaneous Determination of Schizandrol A, Schizandrol B, Schisandrin A, γ-Schisandrin, and Schisandrin C |
| title_full | A Simple and Convenient Method for Simultaneous Determination of Schizandrol A, Schizandrol B, Schisandrin A, γ-Schisandrin, and Schisandrin C |
| title_fullStr | A Simple and Convenient Method for Simultaneous Determination of Schizandrol A, Schizandrol B, Schisandrin A, γ-Schisandrin, and Schisandrin C |
| title_full_unstemmed | A Simple and Convenient Method for Simultaneous Determination of Schizandrol A, Schizandrol B, Schisandrin A, γ-Schisandrin, and Schisandrin C |
| title_short | A Simple and Convenient Method for Simultaneous Determination of Schizandrol A, Schizandrol B, Schisandrin A, γ-Schisandrin, and Schisandrin C |
| title_sort | simple and convenient method for simultaneous determination of schizandrol a schizandrol b schisandrin a γ schisandrin and schisandrin c |
| url | http://dx.doi.org/10.1155/2016/1739879 |
| work_keys_str_mv | AT yuzhou asimpleandconvenientmethodforsimultaneousdeterminationofschizandrolaschizandrolbschisandrinagschisandrinandschisandrinc AT wulingwei asimpleandconvenientmethodforsimultaneousdeterminationofschizandrolaschizandrolbschisandrinagschisandrinandschisandrinc AT jiangxinghua asimpleandconvenientmethodforsimultaneousdeterminationofschizandrolaschizandrolbschisandrinagschisandrinandschisandrinc AT qingshengfan asimpleandconvenientmethodforsimultaneousdeterminationofschizandrolaschizandrolbschisandrinagschisandrinandschisandrinc AT yuzhou simpleandconvenientmethodforsimultaneousdeterminationofschizandrolaschizandrolbschisandrinagschisandrinandschisandrinc AT wulingwei simpleandconvenientmethodforsimultaneousdeterminationofschizandrolaschizandrolbschisandrinagschisandrinandschisandrinc AT jiangxinghua simpleandconvenientmethodforsimultaneousdeterminationofschizandrolaschizandrolbschisandrinagschisandrinandschisandrinc AT qingshengfan simpleandconvenientmethodforsimultaneousdeterminationofschizandrolaschizandrolbschisandrinagschisandrinandschisandrinc |