Greater response to placebo in children than in adults: a systematic review and meta-analysis in drug-resistant partial epilepsy.
<h4>Background</h4>Despite guidelines establishing the need to perform comprehensive paediatric drug development programs, pivotal trials in children with epilepsy have been completed mostly in Phase IV as a postapproval replication of adult data. However, it has been shown that the trea...
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| Main Authors: | Sylvain Rheims, Michel Cucherat, Alexis Arzimanoglou, Philippe Ryvlin |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-08-01
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| Series: | PLoS Medicine |
| Online Access: | https://doi.org/10.1371/journal.pmed.0050166 |
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