The Burden of Cost in Bronchiolitis Obliterans Syndrome: Predictions for the Next Decade
In health economics, costs can be divided into both direct and indirect categories. Direct costs tend to consist of medical costs, which are those directly attributed to health care interventions (e.g., hospitalizations, pharmaceuticals, devices), and non-medical direct costs such as monitoring and...
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| Format: | Article |
| Language: | English |
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Columbia Data Analytics, LLC
2016-06-01
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| Series: | Journal of Health Economics and Outcomes Research |
| Online Access: | https://doi.org/10.36469/9815 |
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| author | Christopher A. Jones David G. Chapman Peter Weimersheimer Luca Fernandez Oscar Alejandro Mesa Christian Peters Bart M. Vanaudenaerde Mitchell C. Norotsky Robin Vos |
| author_facet | Christopher A. Jones David G. Chapman Peter Weimersheimer Luca Fernandez Oscar Alejandro Mesa Christian Peters Bart M. Vanaudenaerde Mitchell C. Norotsky Robin Vos |
| author_sort | Christopher A. Jones |
| collection | DOAJ |
| description | In health economics, costs can be divided into both direct and indirect categories. Direct costs tend to consist of medical costs, which are those directly attributed to health care interventions (e.g., hospitalizations, pharmaceuticals, devices), and non-medical direct costs such as monitoring and professional caregiving. Indirect costs tend to comprise those related to lost productivity due to illness (or treatment), burden on systems outside of the healthcare domain, and other costs that can sometimes outweigh the entire sum of direct healthcare costs.
The most common life-threatening complication of lung and hematopoietic stem-cell transplantation (HSCT) is bronchiolitis obliterans syndrome (BOS). BOS is currently diagnosed as a 20% decline in the forced expiratory volume in one second (FEV1) from the best (baseline) post-transplantation value, and is a major cause of morbidity and mortality amongst lung and stem cell transplant patients. BOS affects half of all lung transplant patients within the first 5 years post-transplant, rising to the majority of patients (~80%) within the first decade following transplant.
We estimated both direct and indirect costs for the first 10 years following BOS diagnosis, a viewpoint that highlights a tremendous imbalance between healthcare and non-healthcare costs. The lost workforce resulting from BOS-related infirmity will cost society more than $3.7 Billion over the next decade, a figure that is more than double the estimated 10-year cost of treating BOS ($1.4B), including diagnostics, immunosuppressives, and additional complications. As such, BOS is estimated to present a burden of cost that must be evaluated in a new light to include the wider societal perspective. |
| format | Article |
| id | doaj-art-fb1d13b426f04723a9ddb4e58d1b60db |
| institution | Kabale University |
| issn | 2327-2236 |
| language | English |
| publishDate | 2016-06-01 |
| publisher | Columbia Data Analytics, LLC |
| record_format | Article |
| series | Journal of Health Economics and Outcomes Research |
| spelling | doaj-art-fb1d13b426f04723a9ddb4e58d1b60db2025-02-10T16:13:19ZengColumbia Data Analytics, LLCJournal of Health Economics and Outcomes Research2327-22362016-06-0142The Burden of Cost in Bronchiolitis Obliterans Syndrome: Predictions for the Next DecadeChristopher A. JonesDavid G. ChapmanPeter WeimersheimerLuca FernandezOscar Alejandro MesaChristian PetersBart M. VanaudenaerdeMitchell C. NorotskyRobin VosIn health economics, costs can be divided into both direct and indirect categories. Direct costs tend to consist of medical costs, which are those directly attributed to health care interventions (e.g., hospitalizations, pharmaceuticals, devices), and non-medical direct costs such as monitoring and professional caregiving. Indirect costs tend to comprise those related to lost productivity due to illness (or treatment), burden on systems outside of the healthcare domain, and other costs that can sometimes outweigh the entire sum of direct healthcare costs. The most common life-threatening complication of lung and hematopoietic stem-cell transplantation (HSCT) is bronchiolitis obliterans syndrome (BOS). BOS is currently diagnosed as a 20% decline in the forced expiratory volume in one second (FEV1) from the best (baseline) post-transplantation value, and is a major cause of morbidity and mortality amongst lung and stem cell transplant patients. BOS affects half of all lung transplant patients within the first 5 years post-transplant, rising to the majority of patients (~80%) within the first decade following transplant. We estimated both direct and indirect costs for the first 10 years following BOS diagnosis, a viewpoint that highlights a tremendous imbalance between healthcare and non-healthcare costs. The lost workforce resulting from BOS-related infirmity will cost society more than $3.7 Billion over the next decade, a figure that is more than double the estimated 10-year cost of treating BOS ($1.4B), including diagnostics, immunosuppressives, and additional complications. As such, BOS is estimated to present a burden of cost that must be evaluated in a new light to include the wider societal perspective.https://doi.org/10.36469/9815 |
| spellingShingle | Christopher A. Jones David G. Chapman Peter Weimersheimer Luca Fernandez Oscar Alejandro Mesa Christian Peters Bart M. Vanaudenaerde Mitchell C. Norotsky Robin Vos The Burden of Cost in Bronchiolitis Obliterans Syndrome: Predictions for the Next Decade Journal of Health Economics and Outcomes Research |
| title | The Burden of Cost in Bronchiolitis Obliterans Syndrome: Predictions for the Next Decade |
| title_full | The Burden of Cost in Bronchiolitis Obliterans Syndrome: Predictions for the Next Decade |
| title_fullStr | The Burden of Cost in Bronchiolitis Obliterans Syndrome: Predictions for the Next Decade |
| title_full_unstemmed | The Burden of Cost in Bronchiolitis Obliterans Syndrome: Predictions for the Next Decade |
| title_short | The Burden of Cost in Bronchiolitis Obliterans Syndrome: Predictions for the Next Decade |
| title_sort | burden of cost in bronchiolitis obliterans syndrome predictions for the next decade |
| url | https://doi.org/10.36469/9815 |
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