A unified-field theory of genome organization and gene regulation

Summary: Our aim is to predict how often genic and non-genic promoters fire within a cell. We first review a parsimonious pan-genomic model for genome organization and gene regulation, where transcription rate is determined by proximity in 3D space of promoters to clusters containing appropriate fac...

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Bibliographic Details
Main Authors: Giuseppe Negro, Massimiliano Semeraro, Peter R. Cook, Davide Marenduzzo
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422402443X
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