Exercise mediates the sex differences in adult visuospatial cognitive ability

BackgroundSex differences in visuospatial cognitive performance have been consistently documented, with males typically demonstrating superior performance in tasks requiring spatial processing. While multiple biological, psychological, and sociocultural factors have been proposed to explain these di...

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Main Authors: Ruiqi Ruan, Junsheng Hong, Yan Huang, Fan Yuan, Xuehao Zhang, Yefei Mo, Tianxiao Hu, Yuhe Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Psychology
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Online Access:https://www.frontiersin.org/articles/10.3389/fpsyg.2025.1629724/full
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author Ruiqi Ruan
Junsheng Hong
Yan Huang
Fan Yuan
Xuehao Zhang
Yefei Mo
Tianxiao Hu
Tianxiao Hu
Yuhe Liu
author_facet Ruiqi Ruan
Junsheng Hong
Yan Huang
Fan Yuan
Xuehao Zhang
Yefei Mo
Tianxiao Hu
Tianxiao Hu
Yuhe Liu
author_sort Ruiqi Ruan
collection DOAJ
description BackgroundSex differences in visuospatial cognitive performance have been consistently documented, with males typically demonstrating superior performance in tasks requiring spatial processing. While multiple biological, psychological, and sociocultural factors have been proposed to explain these differences, the role of physical exercise as a potential mediator remains understudied. Given that females typically engage in less physical exercise than males globally, this study aimed to investigate whether exercise intensity serves as a mediating factor in the observed sex/gender differences in visuospatial cognitive ability.MethodsA total of 224 undergraduate students (112 men and 112 women) aged 18–25 years participated in a comprehensive battery of visuospatial cognitive tests, including assessments of mental rotation, spatial memory, and spatial navigation ability. Participants’ weekly exercise patterns were assessed using the validated Godin-Shephard Leisure-Time Physical Activity Questionnaire, with activities categorized into strenuous, moderate, and mild exercise. Mediation analyses were conducted using the PROCESS macro (Model 4) with 5,000 bootstrap iterations, controlling for spatial anxiety, sense of direction, and childhood spatial activity experience.ResultsMales significantly outperformed females across all visuospatial cognitive domains (all p < 0.05). Mediation analysis revealed that leisure time activity score significantly mediated sex/gender differences in visuospatial cognitive ability, with indirect effects ranging from 20 to 34% of the total effect. When examining exercise intensity separately, strenuous exercise emerged as the primary mediator, particularly in mental rotation (indirect effect = 0.073, 95% CI [0.021, 0.134]) and spatial memory tests (forward span: indirect effect = 0.073, 95% CI [0.017, 0.147]; backward span: indirect effect = 0.069, 95% CI [0.009, 0.143]). The mediating effect of strenuous exercise was more pronounced in tasks with higher cognitive demands.ConclusionPhysical exercise, particularly strenuous exercise, partially mediates sex differences in visuospatial cognitive abilities among young adults. These findings suggest that promoting increased participation in strenuous physical activities among women may help reduce gender disparities in visuospatial cognition. However, the cross-sectional nature of this study precludes causal inferences, and future longitudinal or intervention studies are needed to confirm these relationships.
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spelling doaj-art-fb157801d82544b5b00d42e52df3ff1e2025-08-20T03:36:54ZengFrontiers Media S.A.Frontiers in Psychology1664-10782025-08-011610.3389/fpsyg.2025.16297241629724Exercise mediates the sex differences in adult visuospatial cognitive abilityRuiqi Ruan0Junsheng Hong1Yan Huang2Fan Yuan3Xuehao Zhang4Yefei Mo5Tianxiao Hu6Tianxiao Hu7Yuhe Liu8School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, ChinaDepartment of Otolaryngology, Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaDepartment of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaDepartment of Otolaryngology, Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaDepartment of Otolaryngology, Head and Neck Surgery, Sir Run Run Shaw Hospital, Zhejiang University, Zhejiang, ChinaDepartment of Otolaryngology, Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaCollege of Life Science, Zhejiang Chinese Medical University, Hangzhou, ChinaDepartment of Endocrinology, The 903rd Hospital of PLA, Hangzhou, ChinaDepartment of Otolaryngology, Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaBackgroundSex differences in visuospatial cognitive performance have been consistently documented, with males typically demonstrating superior performance in tasks requiring spatial processing. While multiple biological, psychological, and sociocultural factors have been proposed to explain these differences, the role of physical exercise as a potential mediator remains understudied. Given that females typically engage in less physical exercise than males globally, this study aimed to investigate whether exercise intensity serves as a mediating factor in the observed sex/gender differences in visuospatial cognitive ability.MethodsA total of 224 undergraduate students (112 men and 112 women) aged 18–25 years participated in a comprehensive battery of visuospatial cognitive tests, including assessments of mental rotation, spatial memory, and spatial navigation ability. Participants’ weekly exercise patterns were assessed using the validated Godin-Shephard Leisure-Time Physical Activity Questionnaire, with activities categorized into strenuous, moderate, and mild exercise. Mediation analyses were conducted using the PROCESS macro (Model 4) with 5,000 bootstrap iterations, controlling for spatial anxiety, sense of direction, and childhood spatial activity experience.ResultsMales significantly outperformed females across all visuospatial cognitive domains (all p < 0.05). Mediation analysis revealed that leisure time activity score significantly mediated sex/gender differences in visuospatial cognitive ability, with indirect effects ranging from 20 to 34% of the total effect. When examining exercise intensity separately, strenuous exercise emerged as the primary mediator, particularly in mental rotation (indirect effect = 0.073, 95% CI [0.021, 0.134]) and spatial memory tests (forward span: indirect effect = 0.073, 95% CI [0.017, 0.147]; backward span: indirect effect = 0.069, 95% CI [0.009, 0.143]). The mediating effect of strenuous exercise was more pronounced in tasks with higher cognitive demands.ConclusionPhysical exercise, particularly strenuous exercise, partially mediates sex differences in visuospatial cognitive abilities among young adults. These findings suggest that promoting increased participation in strenuous physical activities among women may help reduce gender disparities in visuospatial cognition. However, the cross-sectional nature of this study precludes causal inferences, and future longitudinal or intervention studies are needed to confirm these relationships.https://www.frontiersin.org/articles/10.3389/fpsyg.2025.1629724/fullexercisegender differencesvisuospatial cognitionmental rotationspatial memoryspatial navigation
spellingShingle Ruiqi Ruan
Junsheng Hong
Yan Huang
Fan Yuan
Xuehao Zhang
Yefei Mo
Tianxiao Hu
Tianxiao Hu
Yuhe Liu
Exercise mediates the sex differences in adult visuospatial cognitive ability
Frontiers in Psychology
exercise
gender differences
visuospatial cognition
mental rotation
spatial memory
spatial navigation
title Exercise mediates the sex differences in adult visuospatial cognitive ability
title_full Exercise mediates the sex differences in adult visuospatial cognitive ability
title_fullStr Exercise mediates the sex differences in adult visuospatial cognitive ability
title_full_unstemmed Exercise mediates the sex differences in adult visuospatial cognitive ability
title_short Exercise mediates the sex differences in adult visuospatial cognitive ability
title_sort exercise mediates the sex differences in adult visuospatial cognitive ability
topic exercise
gender differences
visuospatial cognition
mental rotation
spatial memory
spatial navigation
url https://www.frontiersin.org/articles/10.3389/fpsyg.2025.1629724/full
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