Food-Grade Pickering Emulsions Stabilized by Ultrasound-Treated Foxtail Millet Prolamin: Characterization and <i>In Vitro</i> Release Behavior of Curcumin
To date, extensive studies have focused on developing proteins as stabilizers to fabricate food-grade emulsions for encapsulating bioactive compounds aimed at targeted delivery. This paper aimed to develop a novel stabilizer using foxtail millet prolamin (FMP) to fabricate medium internal-phase Pick...
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MDPI AG
2025-01-01
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| author | Yu Guo Yuewei Luo Zhiyuan Ren Xinpeng Zhang Huiling Duan Zhizong Liu Xiaowen Wang |
| author_facet | Yu Guo Yuewei Luo Zhiyuan Ren Xinpeng Zhang Huiling Duan Zhizong Liu Xiaowen Wang |
| author_sort | Yu Guo |
| collection | DOAJ |
| description | To date, extensive studies have focused on developing proteins as stabilizers to fabricate food-grade emulsions for encapsulating bioactive compounds aimed at targeted delivery. This paper aimed to develop a novel stabilizer using foxtail millet prolamin (FMP) to fabricate medium internal-phase Pickering emulsions (MIPEs) and investigate the stability and <i>in vitro</i> release behavior of curcumin (Cur) encapsulated within the MIPEs. Ultrasound treatment modified the secondary and tertiary structures of FMP, along with its particle size, zeta potential, and wettability, enhancing its functionality as a stabilizer for MIPEs. The MIPEs stabilized by 65% ultrasound-treated FMP (FMP-U) exhibited better rheological properties and stability, significantly improving the storage stability and antioxidant activity of Cur. <i>In vitro</i> digestion results demonstrated that the MIPEs delayed the release of Cur, achieving a final release rate of 84.0 ± 1.47% after 4 h of gastrointestinal digestion and the DPPH radical scavenging activity (RSA) of 39.9 ± 1.31%, which was notably higher than the RSA of free Cur in oil at only 5.8 ± 1.37%. Moreover, MIPEs with Cur increased the bioaccessibility of Cur. This study provides new insights into a novel delivery system designed with FMP-U for encapsulating hydrophobic compounds, thereby enhancing their stability, sustained release, and bioaccessibility. |
| format | Article |
| id | doaj-art-fb13bf9fa9634c7bbef72fbeb97ca051 |
| institution | DOAJ |
| issn | 2304-8158 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
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| series | Foods |
| spelling | doaj-art-fb13bf9fa9634c7bbef72fbeb97ca0512025-08-20T02:48:09ZengMDPI AGFoods2304-81582025-01-0114341710.3390/foods14030417Food-Grade Pickering Emulsions Stabilized by Ultrasound-Treated Foxtail Millet Prolamin: Characterization and <i>In Vitro</i> Release Behavior of CurcuminYu Guo0Yuewei Luo1Zhiyuan Ren2Xinpeng Zhang3Huiling Duan4Zhizong Liu5Xiaowen Wang6College of Food Science and Engineering, Shanxi Agricultural University, Taigu, Jinzhong 030801, ChinaCollege of Food Science and Engineering, Shanxi Agricultural University, Taigu, Jinzhong 030801, ChinaCollege of Food Science and Engineering, Shanxi Agricultural University, Taigu, Jinzhong 030801, ChinaCollege of Food Science and Engineering, Shanxi Agricultural University, Taigu, Jinzhong 030801, ChinaCollege of Food Science and Engineering, Shanxi Agricultural University, Taigu, Jinzhong 030801, ChinaCollege of Food Science and Engineering, Shanxi Agricultural University, Taigu, Jinzhong 030801, ChinaCollege of Food Science and Engineering, Shanxi Agricultural University, Taigu, Jinzhong 030801, ChinaTo date, extensive studies have focused on developing proteins as stabilizers to fabricate food-grade emulsions for encapsulating bioactive compounds aimed at targeted delivery. This paper aimed to develop a novel stabilizer using foxtail millet prolamin (FMP) to fabricate medium internal-phase Pickering emulsions (MIPEs) and investigate the stability and <i>in vitro</i> release behavior of curcumin (Cur) encapsulated within the MIPEs. Ultrasound treatment modified the secondary and tertiary structures of FMP, along with its particle size, zeta potential, and wettability, enhancing its functionality as a stabilizer for MIPEs. The MIPEs stabilized by 65% ultrasound-treated FMP (FMP-U) exhibited better rheological properties and stability, significantly improving the storage stability and antioxidant activity of Cur. <i>In vitro</i> digestion results demonstrated that the MIPEs delayed the release of Cur, achieving a final release rate of 84.0 ± 1.47% after 4 h of gastrointestinal digestion and the DPPH radical scavenging activity (RSA) of 39.9 ± 1.31%, which was notably higher than the RSA of free Cur in oil at only 5.8 ± 1.37%. Moreover, MIPEs with Cur increased the bioaccessibility of Cur. This study provides new insights into a novel delivery system designed with FMP-U for encapsulating hydrophobic compounds, thereby enhancing their stability, sustained release, and bioaccessibility.https://www.mdpi.com/2304-8158/14/3/417foxtail millet prolaminultrasound treatmentmedium internal-phase pickering emulsions (MIPEs)rheological featurecurcumin |
| spellingShingle | Yu Guo Yuewei Luo Zhiyuan Ren Xinpeng Zhang Huiling Duan Zhizong Liu Xiaowen Wang Food-Grade Pickering Emulsions Stabilized by Ultrasound-Treated Foxtail Millet Prolamin: Characterization and <i>In Vitro</i> Release Behavior of Curcumin Foods foxtail millet prolamin ultrasound treatment medium internal-phase pickering emulsions (MIPEs) rheological feature curcumin |
| title | Food-Grade Pickering Emulsions Stabilized by Ultrasound-Treated Foxtail Millet Prolamin: Characterization and <i>In Vitro</i> Release Behavior of Curcumin |
| title_full | Food-Grade Pickering Emulsions Stabilized by Ultrasound-Treated Foxtail Millet Prolamin: Characterization and <i>In Vitro</i> Release Behavior of Curcumin |
| title_fullStr | Food-Grade Pickering Emulsions Stabilized by Ultrasound-Treated Foxtail Millet Prolamin: Characterization and <i>In Vitro</i> Release Behavior of Curcumin |
| title_full_unstemmed | Food-Grade Pickering Emulsions Stabilized by Ultrasound-Treated Foxtail Millet Prolamin: Characterization and <i>In Vitro</i> Release Behavior of Curcumin |
| title_short | Food-Grade Pickering Emulsions Stabilized by Ultrasound-Treated Foxtail Millet Prolamin: Characterization and <i>In Vitro</i> Release Behavior of Curcumin |
| title_sort | food grade pickering emulsions stabilized by ultrasound treated foxtail millet prolamin characterization and i in vitro i release behavior of curcumin |
| topic | foxtail millet prolamin ultrasound treatment medium internal-phase pickering emulsions (MIPEs) rheological feature curcumin |
| url | https://www.mdpi.com/2304-8158/14/3/417 |
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