Analytical Evaluation of Three Portable Blood Glucose Meters for Human Use in Dogs

Portable blood glucose meters (PBGMs) are essential for detecting glycemic disorders. In Brazil, veterinary devices are scarce, and human devices are used as an alternative. This study evaluated the accuracy of three human glucometers: Accu-Chek Guide<sup>®</sup> (ACG), Accu-Chek Guide M...

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Main Authors: José Lucas Xavier Lopes, Taís Bock Nogueira, Luana Rodrigues, Vitória Strzeleski Wodzik, Denise Iparraguirre da Silva, Bruna dos Santos Machado, Álan Gomes Pöppl
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Veterinary Sciences
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Online Access:https://www.mdpi.com/2306-7381/12/5/452
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author José Lucas Xavier Lopes
Taís Bock Nogueira
Luana Rodrigues
Vitória Strzeleski Wodzik
Denise Iparraguirre da Silva
Bruna dos Santos Machado
Álan Gomes Pöppl
author_facet José Lucas Xavier Lopes
Taís Bock Nogueira
Luana Rodrigues
Vitória Strzeleski Wodzik
Denise Iparraguirre da Silva
Bruna dos Santos Machado
Álan Gomes Pöppl
author_sort José Lucas Xavier Lopes
collection DOAJ
description Portable blood glucose meters (PBGMs) are essential for detecting glycemic disorders. In Brazil, veterinary devices are scarce, and human devices are used as an alternative. This study evaluated the accuracy of three human glucometers: Accu-Chek Guide<sup>®</sup> (ACG), Accu-Chek Guide Me<sup>®</sup> (ACGM) (Roche), and EcoCheck<sup>®</sup> (EC) (Eco Diagnóstica). A total of 419 glycemic samples were collected and compared to the glucose oxidase method (GOM), which is considered to be the gold standard. Despite a strong positive correlation compared to the GOM (ACG r = 0.96; ACGM r = 0.9; EC r = 0.89; <i>p</i> < 0.0001), when evaluated by the criteria defined by ISO 15197:2013 for analytical precision, no PG obtained 99% of the readings within the range of +/− 15 for glucose levels < 100 mg/dL and +/− 15% for glucose levels > 100 mg/dL (ACG = 57.9%, ACGM = 47.9%, and EC = 28.4%). ACG was the only PG that fully met the clinical precision criteria according to ISO 15197:2013, with 100% of its measurements in Zones A+B of the error grid. Despite analytical inaccuracy, the ACG PBGM proved to be the best among the devices tested in this study for use in dogs with whole blood samples, not generating any negative impact on animal health.
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spelling doaj-art-fb11694b381e4c7ca948395f5f5de0812025-08-20T01:56:38ZengMDPI AGVeterinary Sciences2306-73812025-05-0112545210.3390/vetsci12050452Analytical Evaluation of Three Portable Blood Glucose Meters for Human Use in DogsJosé Lucas Xavier Lopes0Taís Bock Nogueira1Luana Rodrigues2Vitória Strzeleski Wodzik3Denise Iparraguirre da Silva4Bruna dos Santos Machado5Álan Gomes Pöppl6Veterinary Sciences Post-Graduate Program (PPGCV), Federal University of Rio Grande do Sul (UFRGS), Porto Alegre 91540-000, BrazilVeterinary Sciences Post-Graduate Program (PPGCV), Federal University of Rio Grande do Sul (UFRGS), Porto Alegre 91540-000, BrazilVeterinary Sciences Post-Graduate Program (PPGCV), Federal University of Rio Grande do Sul (UFRGS), Porto Alegre 91540-000, BrazilVeterinary Sciences Post-Graduate Program (PPGCV), Federal University of Rio Grande do Sul (UFRGS), Porto Alegre 91540-000, BrazilFaculty of Veterinary, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre 91540-000, BrazilFaculty of Veterinary, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre 91540-000, BrazilVeterinary Sciences Post-Graduate Program (PPGCV), Federal University of Rio Grande do Sul (UFRGS), Porto Alegre 91540-000, BrazilPortable blood glucose meters (PBGMs) are essential for detecting glycemic disorders. In Brazil, veterinary devices are scarce, and human devices are used as an alternative. This study evaluated the accuracy of three human glucometers: Accu-Chek Guide<sup>®</sup> (ACG), Accu-Chek Guide Me<sup>®</sup> (ACGM) (Roche), and EcoCheck<sup>®</sup> (EC) (Eco Diagnóstica). A total of 419 glycemic samples were collected and compared to the glucose oxidase method (GOM), which is considered to be the gold standard. Despite a strong positive correlation compared to the GOM (ACG r = 0.96; ACGM r = 0.9; EC r = 0.89; <i>p</i> < 0.0001), when evaluated by the criteria defined by ISO 15197:2013 for analytical precision, no PG obtained 99% of the readings within the range of +/− 15 for glucose levels < 100 mg/dL and +/− 15% for glucose levels > 100 mg/dL (ACG = 57.9%, ACGM = 47.9%, and EC = 28.4%). ACG was the only PG that fully met the clinical precision criteria according to ISO 15197:2013, with 100% of its measurements in Zones A+B of the error grid. Despite analytical inaccuracy, the ACG PBGM proved to be the best among the devices tested in this study for use in dogs with whole blood samples, not generating any negative impact on animal health.https://www.mdpi.com/2306-7381/12/5/452International Organization for Standardization 15197:2013blood glucosehypoglycemiahyperglycemiacanine
spellingShingle José Lucas Xavier Lopes
Taís Bock Nogueira
Luana Rodrigues
Vitória Strzeleski Wodzik
Denise Iparraguirre da Silva
Bruna dos Santos Machado
Álan Gomes Pöppl
Analytical Evaluation of Three Portable Blood Glucose Meters for Human Use in Dogs
Veterinary Sciences
International Organization for Standardization 15197:2013
blood glucose
hypoglycemia
hyperglycemia
canine
title Analytical Evaluation of Three Portable Blood Glucose Meters for Human Use in Dogs
title_full Analytical Evaluation of Three Portable Blood Glucose Meters for Human Use in Dogs
title_fullStr Analytical Evaluation of Three Portable Blood Glucose Meters for Human Use in Dogs
title_full_unstemmed Analytical Evaluation of Three Portable Blood Glucose Meters for Human Use in Dogs
title_short Analytical Evaluation of Three Portable Blood Glucose Meters for Human Use in Dogs
title_sort analytical evaluation of three portable blood glucose meters for human use in dogs
topic International Organization for Standardization 15197:2013
blood glucose
hypoglycemia
hyperglycemia
canine
url https://www.mdpi.com/2306-7381/12/5/452
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