Interleukin-18 interacts with NKCC1 to mediate brain injury after intracerebral hemorrhage

Interleukin-18 interacts with NKCC1 to mediate brain injury after intracerebral hemorrhage

Interleukin 18 (IL-18), a proinflammatory cytokine, has been implicated in various neurological disorders, including cerebrovascular disease and psychiatric disorders. In a previous study, IL-18 was observed to activate microglia and enhance the inflammatory response following intracranial hemorrhag...

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Bibliographic Details
Main Authors: Beibei Xu, Hao Li, He Zheng, Zhongyu Gao, Zhigang Miao, Xingshun Xu, Hao Yang, Yi Yang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Interleukin-18
Intracerebral hemorrhage
Brain injury
Microglia
NKCC1
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354624001686
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