Leveraging Tumor Microenvironment to Boost Synergistic Photodynamic Therapy, Ferroptosis Anti‐Tumor Efficiency Based on a Functional Iridium(III) Complex

Leveraging Tumor Microenvironment to Boost Synergistic Photodynamic Therapy, Ferroptosis Anti‐Tumor Efficiency Based on a Functional Iridium(III) Complex

Abstract The tumor microenvironment (TME) severely limits the efficacy of clinical applications of photodynamic therapy (PDT). The development of a functional agent allowing full use of the TME to boost synergistic PDT and ferroptosis anti‐tumor efficiency is an appealing yet significantly challengi...

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Bibliographic Details
Main Authors: Yu Pei, Yinzhen Pan, Zhijun Zhang, Jun Zhu, Yan Sun, Qian Zhang, Dongxia Zhu, Guangzhe Li, Martin R. Bryce, Dong Wang, Ben Zhong Tang
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
Fenton reaction
ferrocene
ferroptosis
iridium(III) complex
photodynamic therapy
Online Access:https://doi.org/10.1002/advs.202413879
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