Blood-brain barrier disruption mediates the association between cerebral small vessel disease and clinical outcome after stroke: a secondary analysis of the Lesion Evolution in Stroke and Ischemia on Neuroimaging study

Blood-brain barrier disruption mediates the association between cerebral small vessel disease and clinical outcome after stroke: a secondary analysis of the Lesion Evolution in Stroke and Ischemia on Neuroimaging study

IntroductionWhite matter hyperintensities (WMH) in patients presenting with acute ischemic stroke are associated with worse clinical outcomes, but the mechanisms underlying this association are unclear. The purpose of this study was to determine whether blood-brain barrier (BBB) disruption, detected...

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Bibliographic Details
Main Authors: Derrick N. Okine, Kyle C. Kern, Marie Luby, Lawrence L. Latour, Rebecca F. Gottesman
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Stroke
Subjects:
HARM
white matter hyperintensities
cerebral small vessel disease
ischemic stroke
post-stroke outcome
Online Access:https://www.frontiersin.org/articles/10.3389/fstro.2024.1510359/full
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