RASGRP2 Suppresses Apoptosis via Inhibition of ROS Production in Vascular Endothelial Cells

We have identified ras guanyl releasing protein 2 (rasgrp2) as a blood vessel related gene from Xenopus embryo. In addition, we reported that RASGRP2 is also expressed in human umbilical vein endothelial cells (HUVEC). It is known that RASGRP2 activates Ras-related protein 1 (Rap1). However, the fun...

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Bibliographic Details
Main Authors: Takuma Sato, Jun-ichi Takino, Kentaro Nagamine, Kazuto Nishio, Takamitsu Hori
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2019/4639165
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