Emerging role and function of Hippo-YAP/TAZ signaling pathway in musculoskeletal disorders

Emerging role and function of Hippo-YAP/TAZ signaling pathway in musculoskeletal disorders

Abstract Hippo pathway is an evolutionarily conservative key pathway that regulates organ size and tissue regeneration by regulating cell proliferation, differentiation and apoptosis. Yes-associated protein 1 (YAP)/ WW domain-containing transcription regulator 1 (TAZ) serves as a pivotal transcripti...

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Bibliographic Details
Main Authors: Juanjuan Han, Jiale Zhang, Xiaoyi Zhang, Wenxin Luo, Lifei Liu, Yuqing Zhu, Qingfeng Liu, Xin-an Zhang
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Stem Cell Research & Therapy
Subjects:
Hippo
YAP/TAZ
Musculoskeletal diseases
Osteoblast
Osteoclast
Cartilage
Online Access:https://doi.org/10.1186/s13287-024-04011-9
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