Development of reference intervals for serum biochemistry in female Hanwoo cattle with different reproductive status

Background: Hanwoo cattle, an indigenous Korean breed, have become economically significant due to genetic improvements and large-scale farming. As individual cow value increases, understanding their unique physiology across different life stages is crucial for optimal health management. This retros...

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Main Authors: Sung-Ho Kim, Tae-Gyun Kim, Sang-Yup Lee, Saet-Byul Kim, Young-Bum Son, Seung-Joon Kim, Won-Jae Lee
Format: Article
Language:English
Published: The Korean Society of Animal Reproduction and Biotechnology 2025-03-01
Series:Journal of Animal Reproduction and Biotechnology
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Online Access:https://www.e-jarb.org/journal/view.html?uid=2720&vmd=Full
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author Sung-Ho Kim
Tae-Gyun Kim
Sang-Yup Lee
Saet-Byul Kim
Young-Bum Son
Seung-Joon Kim
Won-Jae Lee
author_facet Sung-Ho Kim
Tae-Gyun Kim
Sang-Yup Lee
Saet-Byul Kim
Young-Bum Son
Seung-Joon Kim
Won-Jae Lee
author_sort Sung-Ho Kim
collection DOAJ
description Background: Hanwoo cattle, an indigenous Korean breed, have become economically significant due to genetic improvements and large-scale farming. As individual cow value increases, understanding their unique physiology across different life stages is crucial for optimal health management. This retrospective study aimed to investigate serum biochemistry differences among non-pregnant, pregnant, and fattening female Hanwoo cattle and establish breed-specific reference intervals (RIs) for accurate health assessment, utilizing data obtained from routine veterinary care. Methods: Blood samples were collected from female Hanwoo cattle, categorized as pregnant (n = 12), non-pregnant (n = 25), and fattening (n = 11). Eighteen serum biochemical parameters were analyzed and descriptive statistics were calculated for each group. The new RIs in different reproductive status of female Hanwoo were established using the Reference Value Advisor program. Results: Significant differences based on reproductive status were identified in blood urea nitrogen (BUN), γ-glutamyl transferase (GGT), triglyceride (TG), glucose (GLU), and creatinine (CRE) levels. BUN, GGT, and TG levels were significantly higher in fattening cattle compared to pregnant and non-pregnant cows. GLU levels increased progressively across pregnant, non-pregnant, and fattening groups, while CRE levels were significantly higher in pregnant cows. Based on values of biochemical parameters, new RI were suggested for sixteen biochemical parameters, encompassing all three reproductive stages. Conclusions: This study established new RIs for female Hanwoo cattle across nonpregnant, pregnant, and fattening stages, providing a more accurate basis for health assessment and management. These findings will contribute to improved individual cow management, supporting genetic improvement efforts, and enhancing overall herd health in female Hanwoo cattle.
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publishDate 2025-03-01
publisher The Korean Society of Animal Reproduction and Biotechnology
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spelling doaj-art-fab44a28da3c4d8da37e7b69974c796e2025-08-20T03:41:01ZengThe Korean Society of Animal Reproduction and BiotechnologyJournal of Animal Reproduction and Biotechnology2671-46392671-46632025-03-01401122110.12750/JARB.40.1.12Development of reference intervals for serum biochemistry in female Hanwoo cattle with different reproductive statusSung-Ho Kim0https://orcid.org/0000-0001-9088-9840Tae-Gyun Kim1https://orcid.org/0009-0005-8222-2516Sang-Yup Lee2https://orcid.org/0009-0001-9815-7879Saet-Byul Kim3https://orcid.org/0000-0001-8172-186XYoung-Bum Son4https://orcid.org/0000-0002-9581-9339Seung-Joon Kim5https://orcid.org/0000-0002-8521-8898Won-Jae Lee6https://orcid.org/0000-0003-1462-7798College of Veterinary Medicine, Kyungpook National University, Daegu 41566, KoreaCollege of Veterinary Medicine, Kyungpook National University, Daegu 41566, KoreaCollege of Veterinary Medicine, Kyungpook National University, Daegu 41566, KoreaBovivet, Gumi 39133, KoreaCollege of Veterinary Medicine, Chonnam National University, Gwangju 61186, KoreaCollege of Veterinary Medicine, Kyungpook National University, Daegu 41566, KoreaCollege of Veterinary Medicine, Kyungpook National University, Daegu 41566, KoreaBackground: Hanwoo cattle, an indigenous Korean breed, have become economically significant due to genetic improvements and large-scale farming. As individual cow value increases, understanding their unique physiology across different life stages is crucial for optimal health management. This retrospective study aimed to investigate serum biochemistry differences among non-pregnant, pregnant, and fattening female Hanwoo cattle and establish breed-specific reference intervals (RIs) for accurate health assessment, utilizing data obtained from routine veterinary care. Methods: Blood samples were collected from female Hanwoo cattle, categorized as pregnant (n = 12), non-pregnant (n = 25), and fattening (n = 11). Eighteen serum biochemical parameters were analyzed and descriptive statistics were calculated for each group. The new RIs in different reproductive status of female Hanwoo were established using the Reference Value Advisor program. Results: Significant differences based on reproductive status were identified in blood urea nitrogen (BUN), γ-glutamyl transferase (GGT), triglyceride (TG), glucose (GLU), and creatinine (CRE) levels. BUN, GGT, and TG levels were significantly higher in fattening cattle compared to pregnant and non-pregnant cows. GLU levels increased progressively across pregnant, non-pregnant, and fattening groups, while CRE levels were significantly higher in pregnant cows. Based on values of biochemical parameters, new RI were suggested for sixteen biochemical parameters, encompassing all three reproductive stages. Conclusions: This study established new RIs for female Hanwoo cattle across nonpregnant, pregnant, and fattening stages, providing a more accurate basis for health assessment and management. These findings will contribute to improved individual cow management, supporting genetic improvement efforts, and enhancing overall herd health in female Hanwoo cattle.https://www.e-jarb.org/journal/view.html?uid=2720&vmd=Fullhanwooreference intervalsreference value advisorreproductive statusserum biochemistry
spellingShingle Sung-Ho Kim
Tae-Gyun Kim
Sang-Yup Lee
Saet-Byul Kim
Young-Bum Son
Seung-Joon Kim
Won-Jae Lee
Development of reference intervals for serum biochemistry in female Hanwoo cattle with different reproductive status
Journal of Animal Reproduction and Biotechnology
hanwoo
reference intervals
reference value advisor
reproductive status
serum biochemistry
title Development of reference intervals for serum biochemistry in female Hanwoo cattle with different reproductive status
title_full Development of reference intervals for serum biochemistry in female Hanwoo cattle with different reproductive status
title_fullStr Development of reference intervals for serum biochemistry in female Hanwoo cattle with different reproductive status
title_full_unstemmed Development of reference intervals for serum biochemistry in female Hanwoo cattle with different reproductive status
title_short Development of reference intervals for serum biochemistry in female Hanwoo cattle with different reproductive status
title_sort development of reference intervals for serum biochemistry in female hanwoo cattle with different reproductive status
topic hanwoo
reference intervals
reference value advisor
reproductive status
serum biochemistry
url https://www.e-jarb.org/journal/view.html?uid=2720&vmd=Full
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AT sangyuplee developmentofreferenceintervalsforserumbiochemistryinfemalehanwoocattlewithdifferentreproductivestatus
AT saetbyulkim developmentofreferenceintervalsforserumbiochemistryinfemalehanwoocattlewithdifferentreproductivestatus
AT youngbumson developmentofreferenceintervalsforserumbiochemistryinfemalehanwoocattlewithdifferentreproductivestatus
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