Geriatric Psoriasis: Evaluation of Clinical Features, Disease Course, and Treatment Modalities of Patients from a Tertiary Care Hospital
Introduction: Psoriasis is an inflammatory skin disease characterized by erythematous, scaly, and well-demarcated pruritic plaques on the extensor areas of the extremities. Psoriasis is one of the most common dermatological diseases in the geriatric population. Objective: The aim of this investig...
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Mattioli1885
2025-01-01
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| Series: | Dermatology Practical & Conceptual |
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| Online Access: | https://dpcj.org/index.php/dpc/article/view/4511 |
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| author | Elif Çalışkan Yusuf Can Edek Nuray Keskin Petek Üstün Esra Adışen |
| author_facet | Elif Çalışkan Yusuf Can Edek Nuray Keskin Petek Üstün Esra Adışen |
| author_sort | Elif Çalışkan |
| collection | DOAJ |
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Introduction: Psoriasis is an inflammatory skin disease characterized by erythematous, scaly, and well-demarcated pruritic plaques on the extensor areas of the extremities. Psoriasis is one of the most common dermatological diseases in the geriatric population.
Objective: The aim of this investigation is to evaluate the demographic data, clinical characteristics, and treatment responses of the geriatric population (≥60 with psoriasis at our hospital.
Methods: In this study, we examined 221 geriatric patients diagnosed with psoriasis. We evaluated patients in 2 groups: early-onset (<60 years) and elderly-onset (≥60 years).
Results: In our study, 50.7% of the patients were female, the average age was 65.9 years., and 76.4% of the patients were considered early-onset. There was no significant difference in terms of the initial body areas affected by the disease between the early-onset and elderly-onset groups; 45.7% of patients had nail psoriasis, while 27.1% had psoriatic arthritis. Nail involvement (p = 0.021) and the presence of psoriatic arthritis (p = 0.011) were more common in the early-onset group. Systemic treatment was predominantly initiated as the first treatment agent in the elderly-onset group (p = 0.014). Patients in the early-onset group received more cyclosporine treatment than the others (p=0.01).
Conclusions: The geriatric population is associated with multiple comorbidities and polypharmacy, highlighting the importance of evaluating patients' medications and comorbidities when selecting a treatment agent for psoriasis.
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| format | Article |
| id | doaj-art-fab17d9a2ad44f79b87f9a40c8113d0f |
| institution | OA Journals |
| issn | 2160-9381 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Mattioli1885 |
| record_format | Article |
| series | Dermatology Practical & Conceptual |
| spelling | doaj-art-fab17d9a2ad44f79b87f9a40c8113d0f2025-08-20T02:30:28ZengMattioli1885Dermatology Practical & Conceptual2160-93812025-01-0115110.5826/dpc.1501a4511Geriatric Psoriasis: Evaluation of Clinical Features, Disease Course, and Treatment Modalities of Patients from a Tertiary Care HospitalElif Çalışkan0Yusuf Can Edek1Nuray Keskin2Petek Üstün3Esra Adışen4Gazi University Faculty of MedicineGazi University Faculty of MedicineYenimahalle Training and Research HospitalGazi University Faculty of MedicineGazi University Faculty of Medicine Introduction: Psoriasis is an inflammatory skin disease characterized by erythematous, scaly, and well-demarcated pruritic plaques on the extensor areas of the extremities. Psoriasis is one of the most common dermatological diseases in the geriatric population. Objective: The aim of this investigation is to evaluate the demographic data, clinical characteristics, and treatment responses of the geriatric population (≥60 with psoriasis at our hospital. Methods: In this study, we examined 221 geriatric patients diagnosed with psoriasis. We evaluated patients in 2 groups: early-onset (<60 years) and elderly-onset (≥60 years). Results: In our study, 50.7% of the patients were female, the average age was 65.9 years., and 76.4% of the patients were considered early-onset. There was no significant difference in terms of the initial body areas affected by the disease between the early-onset and elderly-onset groups; 45.7% of patients had nail psoriasis, while 27.1% had psoriatic arthritis. Nail involvement (p = 0.021) and the presence of psoriatic arthritis (p = 0.011) were more common in the early-onset group. Systemic treatment was predominantly initiated as the first treatment agent in the elderly-onset group (p = 0.014). Patients in the early-onset group received more cyclosporine treatment than the others (p=0.01). Conclusions: The geriatric population is associated with multiple comorbidities and polypharmacy, highlighting the importance of evaluating patients' medications and comorbidities when selecting a treatment agent for psoriasis. https://dpcj.org/index.php/dpc/article/view/4511psoriasisPalmoplantar psoriasisKeratodermaQuality of life |
| spellingShingle | Elif Çalışkan Yusuf Can Edek Nuray Keskin Petek Üstün Esra Adışen Geriatric Psoriasis: Evaluation of Clinical Features, Disease Course, and Treatment Modalities of Patients from a Tertiary Care Hospital Dermatology Practical & Conceptual psoriasis Palmoplantar psoriasis Keratoderma Quality of life |
| title | Geriatric Psoriasis: Evaluation of Clinical Features, Disease Course, and Treatment Modalities of Patients from a Tertiary Care Hospital |
| title_full | Geriatric Psoriasis: Evaluation of Clinical Features, Disease Course, and Treatment Modalities of Patients from a Tertiary Care Hospital |
| title_fullStr | Geriatric Psoriasis: Evaluation of Clinical Features, Disease Course, and Treatment Modalities of Patients from a Tertiary Care Hospital |
| title_full_unstemmed | Geriatric Psoriasis: Evaluation of Clinical Features, Disease Course, and Treatment Modalities of Patients from a Tertiary Care Hospital |
| title_short | Geriatric Psoriasis: Evaluation of Clinical Features, Disease Course, and Treatment Modalities of Patients from a Tertiary Care Hospital |
| title_sort | geriatric psoriasis evaluation of clinical features disease course and treatment modalities of patients from a tertiary care hospital |
| topic | psoriasis Palmoplantar psoriasis Keratoderma Quality of life |
| url | https://dpcj.org/index.php/dpc/article/view/4511 |
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