EXPERIENCE OF USING THE MINIMUM INHIBITORY CONCENTRATION METHOD ON LIQUID NUTRITIONAL MEDIA FOR DRUG SUSCEPTIBILITY TESTING OF NON-TUBERCULOUS MYCOBACTERIA
Goal of the study: analysis of drug resistance of certain species of non-tuberculous mycobacteria through testing by minimum inhibitory concentrations on the fluid nutritional media.Materials and method: drug resistance of non-tuberculous mycobacteria was tested by the method of minimum inhibitory c...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2017-09-01
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| Series: | Туберкулез и болезни лёгких |
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| Online Access: | https://www.tibl-journal.com/jour/article/view/1036 |
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| author | O. I. Alkhovik T. I. Petrenko |
| author_facet | O. I. Alkhovik T. I. Petrenko |
| author_sort | O. I. Alkhovik |
| collection | DOAJ |
| description | Goal of the study: analysis of drug resistance of certain species of non-tuberculous mycobacteria through testing by minimum inhibitory concentrations on the fluid nutritional media.Materials and method: drug resistance of non-tuberculous mycobacteria was tested by the method of minimum inhibitory concentrations on the fluid nutritional media. 51 strains of non-tuberculous mycobacteria from the species of M. intracellulare, M. avium, M. kansasii, M. gordonae, M. fortuitum, M. abscessus were tested. The minimum inhibitory concentration of the drug for slow-growing non-tuberculous mycobacteria was defined using the panel of 13 drugs (SLOWMYCO) and for the fast-growing mycobacteria – the panel of 15 drugs RAPMYCO Sensititre (Trek Diagnostic System, Thermo Scientific, USA) was used. It was proved that the majority of tested fast growing mycobacteria were resistant to ceftriaxone, cefepime, cefoxitin but susceptible to amikacin; and slow growing non-tuberculous mycobacteria were susceptible to clarithromycin, linezolid and amikacin. |
| format | Article |
| id | doaj-art-fa973922e1d64a758ef3b31ff9b447ec |
| institution | OA Journals |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| publishDate | 2017-09-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj-art-fa973922e1d64a758ef3b31ff9b447ec2025-08-20T01:47:52ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062017-09-01958586210.21292/2075-1230-2017-95-8-58-621036EXPERIENCE OF USING THE MINIMUM INHIBITORY CONCENTRATION METHOD ON LIQUID NUTRITIONAL MEDIA FOR DRUG SUSCEPTIBILITY TESTING OF NON-TUBERCULOUS MYCOBACTERIAO. I. Alkhovik0T. I. Petrenko1Novosibirsk Tuberculosis Research InstituteNovosibirsk State Medical UniversityGoal of the study: analysis of drug resistance of certain species of non-tuberculous mycobacteria through testing by minimum inhibitory concentrations on the fluid nutritional media.Materials and method: drug resistance of non-tuberculous mycobacteria was tested by the method of minimum inhibitory concentrations on the fluid nutritional media. 51 strains of non-tuberculous mycobacteria from the species of M. intracellulare, M. avium, M. kansasii, M. gordonae, M. fortuitum, M. abscessus were tested. The minimum inhibitory concentration of the drug for slow-growing non-tuberculous mycobacteria was defined using the panel of 13 drugs (SLOWMYCO) and for the fast-growing mycobacteria – the panel of 15 drugs RAPMYCO Sensititre (Trek Diagnostic System, Thermo Scientific, USA) was used. It was proved that the majority of tested fast growing mycobacteria were resistant to ceftriaxone, cefepime, cefoxitin but susceptible to amikacin; and slow growing non-tuberculous mycobacteria were susceptible to clarithromycin, linezolid and amikacin.https://www.tibl-journal.com/jour/article/view/1036drug resistancenon-tuberculous mycobacteriaminimum inhibitory concentration |
| spellingShingle | O. I. Alkhovik T. I. Petrenko EXPERIENCE OF USING THE MINIMUM INHIBITORY CONCENTRATION METHOD ON LIQUID NUTRITIONAL MEDIA FOR DRUG SUSCEPTIBILITY TESTING OF NON-TUBERCULOUS MYCOBACTERIA Туберкулез и болезни лёгких drug resistance non-tuberculous mycobacteria minimum inhibitory concentration |
| title | EXPERIENCE OF USING THE MINIMUM INHIBITORY CONCENTRATION METHOD ON LIQUID NUTRITIONAL MEDIA FOR DRUG SUSCEPTIBILITY TESTING OF NON-TUBERCULOUS MYCOBACTERIA |
| title_full | EXPERIENCE OF USING THE MINIMUM INHIBITORY CONCENTRATION METHOD ON LIQUID NUTRITIONAL MEDIA FOR DRUG SUSCEPTIBILITY TESTING OF NON-TUBERCULOUS MYCOBACTERIA |
| title_fullStr | EXPERIENCE OF USING THE MINIMUM INHIBITORY CONCENTRATION METHOD ON LIQUID NUTRITIONAL MEDIA FOR DRUG SUSCEPTIBILITY TESTING OF NON-TUBERCULOUS MYCOBACTERIA |
| title_full_unstemmed | EXPERIENCE OF USING THE MINIMUM INHIBITORY CONCENTRATION METHOD ON LIQUID NUTRITIONAL MEDIA FOR DRUG SUSCEPTIBILITY TESTING OF NON-TUBERCULOUS MYCOBACTERIA |
| title_short | EXPERIENCE OF USING THE MINIMUM INHIBITORY CONCENTRATION METHOD ON LIQUID NUTRITIONAL MEDIA FOR DRUG SUSCEPTIBILITY TESTING OF NON-TUBERCULOUS MYCOBACTERIA |
| title_sort | experience of using the minimum inhibitory concentration method on liquid nutritional media for drug susceptibility testing of non tuberculous mycobacteria |
| topic | drug resistance non-tuberculous mycobacteria minimum inhibitory concentration |
| url | https://www.tibl-journal.com/jour/article/view/1036 |
| work_keys_str_mv | AT oialkhovik experienceofusingtheminimuminhibitoryconcentrationmethodonliquidnutritionalmediafordrugsusceptibilitytestingofnontuberculousmycobacteria AT tipetrenko experienceofusingtheminimuminhibitoryconcentrationmethodonliquidnutritionalmediafordrugsusceptibilitytestingofnontuberculousmycobacteria |