Valorization of Mexican prickly pear cladodes (Opuntia spp) as a source of antifungal compounds against phytopathogenic strains

Prickly pear cactus (Opuntia spp.) has been widely consumed in Mexico as an important source of nutrients in the diet. Older, larger, and fibrous cladodes lose commercial interest for human consumption, resulting in a by-product rich in different bioactive compounds. In this work, the optimization o...

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Main Authors: Vicente Antonio Mirón-Mérida, Martha Angélica Pardo-Islas, Jorge Yañez-Fernández, Paulina Gutiérrez-Macías, Blanca Estela Barragán-Huerta
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:CyTA - Journal of Food
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Online Access:https://www.tandfonline.com/doi/10.1080/19476337.2025.2544932
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author Vicente Antonio Mirón-Mérida
Martha Angélica Pardo-Islas
Jorge Yañez-Fernández
Paulina Gutiérrez-Macías
Blanca Estela Barragán-Huerta
author_facet Vicente Antonio Mirón-Mérida
Martha Angélica Pardo-Islas
Jorge Yañez-Fernández
Paulina Gutiérrez-Macías
Blanca Estela Barragán-Huerta
author_sort Vicente Antonio Mirón-Mérida
collection DOAJ
description Prickly pear cactus (Opuntia spp.) has been widely consumed in Mexico as an important source of nutrients in the diet. Older, larger, and fibrous cladodes lose commercial interest for human consumption, resulting in a by-product rich in different bioactive compounds. In this work, the optimization of a microwave pretreatment combined with a reflux extraction of antioxidants from Opuntia spp cladodes was performed. The optimal factors were the liquid/solid ratio (24 mL/g), ethanol percentage (25%), and microwave pre-treatment time (3.88 min), with a phenolic content, antioxidant activity, and extract yield of 33.47 g GA/kg, 259.66 µmol Trolox/g, and 4.16%, respectively. The design was validated with fit percentages between 90.14% and 97.80%. The optimized extract exhibited growth inhibition against Colletotrichum gloesosporioides (85.27%), Fusarium verticillioides (58.47%), and Helminthosporium sp (77.87%). Furthermore, gallic acid, protocatechuic acid, rutin, myricetin, isorhamnetin, sinapic acid, and kaempferol were identified in the extract.
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issn 1947-6337
1947-6345
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publishDate 2025-12-01
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spelling doaj-art-fa9236ceb7764850a3d51dc8aaf8db372025-08-20T04:03:26ZengTaylor & Francis GroupCyTA - Journal of Food1947-63371947-63452025-12-0123110.1080/19476337.2025.2544932Valorization of Mexican prickly pear cladodes (Opuntia spp) as a source of antifungal compounds against phytopathogenic strainsVicente Antonio Mirón-Mérida0Martha Angélica Pardo-Islas1Jorge Yañez-Fernández2Paulina Gutiérrez-Macías3Blanca Estela Barragán-Huerta4Departamento de Bioingeniería, Escuela de Ingeniería y Ciencias, Tecnologico de Monterrey, Colonia Tecnológico, Monterrey, MexicoDepartamento de Ingeniería en Sistemas Ambientales, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Av. Wilfrido Massieu S/n, Unidad Profesional Adolfo López Mateos, Ciudad de México, MexicoLaboratorio de Biomateriales, Centro de Investigación en Ciencia Aplicada y Tecnología Avanzada Unidad Legaria, Instituto Politécnico Nacional, Legaria 694 Col, Irrigación, Ciudad de México, MexicoDepartamento de Ingeniería en Sistemas Ambientales, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Av. Wilfrido Massieu S/n, Unidad Profesional Adolfo López Mateos, Ciudad de México, MexicoDepartamento de Ingeniería en Sistemas Ambientales, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Av. Wilfrido Massieu S/n, Unidad Profesional Adolfo López Mateos, Ciudad de México, MexicoPrickly pear cactus (Opuntia spp.) has been widely consumed in Mexico as an important source of nutrients in the diet. Older, larger, and fibrous cladodes lose commercial interest for human consumption, resulting in a by-product rich in different bioactive compounds. In this work, the optimization of a microwave pretreatment combined with a reflux extraction of antioxidants from Opuntia spp cladodes was performed. The optimal factors were the liquid/solid ratio (24 mL/g), ethanol percentage (25%), and microwave pre-treatment time (3.88 min), with a phenolic content, antioxidant activity, and extract yield of 33.47 g GA/kg, 259.66 µmol Trolox/g, and 4.16%, respectively. The design was validated with fit percentages between 90.14% and 97.80%. The optimized extract exhibited growth inhibition against Colletotrichum gloesosporioides (85.27%), Fusarium verticillioides (58.47%), and Helminthosporium sp (77.87%). Furthermore, gallic acid, protocatechuic acid, rutin, myricetin, isorhamnetin, sinapic acid, and kaempferol were identified in the extract.https://www.tandfonline.com/doi/10.1080/19476337.2025.2544932Prickly pear cladodesantifungal activityphenolic compoundsantioxidantsmicrowave pretreatmentexperimental design
spellingShingle Vicente Antonio Mirón-Mérida
Martha Angélica Pardo-Islas
Jorge Yañez-Fernández
Paulina Gutiérrez-Macías
Blanca Estela Barragán-Huerta
Valorization of Mexican prickly pear cladodes (Opuntia spp) as a source of antifungal compounds against phytopathogenic strains
CyTA - Journal of Food
Prickly pear cladodes
antifungal activity
phenolic compounds
antioxidants
microwave pretreatment
experimental design
title Valorization of Mexican prickly pear cladodes (Opuntia spp) as a source of antifungal compounds against phytopathogenic strains
title_full Valorization of Mexican prickly pear cladodes (Opuntia spp) as a source of antifungal compounds against phytopathogenic strains
title_fullStr Valorization of Mexican prickly pear cladodes (Opuntia spp) as a source of antifungal compounds against phytopathogenic strains
title_full_unstemmed Valorization of Mexican prickly pear cladodes (Opuntia spp) as a source of antifungal compounds against phytopathogenic strains
title_short Valorization of Mexican prickly pear cladodes (Opuntia spp) as a source of antifungal compounds against phytopathogenic strains
title_sort valorization of mexican prickly pear cladodes opuntia spp as a source of antifungal compounds against phytopathogenic strains
topic Prickly pear cladodes
antifungal activity
phenolic compounds
antioxidants
microwave pretreatment
experimental design
url https://www.tandfonline.com/doi/10.1080/19476337.2025.2544932
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