Combination of dexmedetomidine and esketamine for postoperative nausea and vomiting in patients undergoing laparoscopic surgery: study protocol for a prospective, randomized, controlled trial

Combination of dexmedetomidine and esketamine for postoperative nausea and vomiting in patients undergoing laparoscopic surgery: study protocol for a prospective, randomized, controlled trial

Abstract Background Laparoscopic surgery has gained widespread acceptance due to its advantages over traditional open procedures, including less postoperative pain and faster recovery. However, postoperative nausea and vomiting (PONV) remains a prevalent complication, affecting up to 80% of high-ris...

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Bibliographic Details
Main Authors: Ying Zhou, Ziyi Shen, Jinbiao Li, Hui Cao, Xinggen Zhou, Weicheng Jin, Ming Yao, Jing Chi, Jie Wang, Chao Zhang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Trials
Subjects:
Laparoscopic surgery
Postoperative nausea and vomiting
Esketamine
Dexmedetomidine
General anesthesia
Online Access:https://doi.org/10.1186/s13063-025-08935-2
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