Antenatal screening of depressive and manic symptoms in south Brazilian childbearing women: A transversal study in advance of the pandemic scenario.

<h4>Background</h4>The diagnosis of mood disorders (MD) during pregnancy is challenging and may bring negative consequences to the maternal-fetal binomial. The long waitlist for specialized psychiatric evaluation in Brazil contributes to the treatment omission. Almost 20.0% of women trea...

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Main Authors: Fernanda Schier de Fraga, Beatriz Souza Lima Wan-Dall, Gabriel Henrique de Oliveira Garcia, Henrique Pandolfo, Adelyne Mayara Tavares da Silva Sequinel, Pedro Alvin, Eduardo Jonson Serman, Vivian Ferreira do Amaral
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0261874&type=printable
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author Fernanda Schier de Fraga
Beatriz Souza Lima Wan-Dall
Gabriel Henrique de Oliveira Garcia
Henrique Pandolfo
Adelyne Mayara Tavares da Silva Sequinel
Pedro Alvin
Eduardo Jonson Serman
Vivian Ferreira do Amaral
author_facet Fernanda Schier de Fraga
Beatriz Souza Lima Wan-Dall
Gabriel Henrique de Oliveira Garcia
Henrique Pandolfo
Adelyne Mayara Tavares da Silva Sequinel
Pedro Alvin
Eduardo Jonson Serman
Vivian Ferreira do Amaral
author_sort Fernanda Schier de Fraga
collection DOAJ
description <h4>Background</h4>The diagnosis of mood disorders (MD) during pregnancy is challenging and may bring negative consequences to the maternal-fetal binomial. The long waitlist for specialized psychiatric evaluation in Brazil contributes to the treatment omission. Almost 20.0% of women treated with antidepressants have a positive screening for bipolar disorder. Therefore, it has been recommended the investigation of depressive and bipolar disorder during prenatal care. Unfortunately, the screening for mood disorders is not a reality in Brazil and many childbearing women remain undiagnosed. The objective of this study is to observe the frequency of MD and the effectiveness of screening scales for routine use by health professionals during prenatal care in high-risk pregnancies.<h4>Methodology/principal findings</h4>This cross-sectional study included 61 childbearing women in their second trimester who were interviewed using the Edinburgh Postnatal Depression Scale (EPDS) and the Mood Disorder Questionnaire (MDQ). The cut-off point was EPDS ≥ 13 and MDQ ≥ 7 and the SCID-5 was the gold standard diagnosis. MD were diagnosed in 24.6% of the high-risk pregnancies. EDPS was positive in 19.7% and the frequency of major depression was 8.2%. 16.4% of the childbearing women were diagnosed with bipolar disorder, while MDQ was positive in 36.1%. 11.5% of the women had EPDS and MDQ positive. EPDS sensitivity was 80.0% and specificity 92.1%, whereas MDQ presented a sensitivity of 70.0% and specificity of 70.6%.<h4>Conclusion/significance</h4>There is a high prevalence of MD in high-risk pregnancies. The routine use of EPDS simultaneously to MDQ during antenatal care is effective and plays an important role in early diagnosis, counselling, and promotion of perinatal mental health.
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spelling doaj-art-fa8e253829e64beb86f2dd6c755c46b42025-08-20T03:00:59ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-011612e026187410.1371/journal.pone.0261874Antenatal screening of depressive and manic symptoms in south Brazilian childbearing women: A transversal study in advance of the pandemic scenario.Fernanda Schier de FragaBeatriz Souza Lima Wan-DallGabriel Henrique de Oliveira GarciaHenrique PandolfoAdelyne Mayara Tavares da Silva SequinelPedro AlvinEduardo Jonson SermanVivian Ferreira do Amaral<h4>Background</h4>The diagnosis of mood disorders (MD) during pregnancy is challenging and may bring negative consequences to the maternal-fetal binomial. The long waitlist for specialized psychiatric evaluation in Brazil contributes to the treatment omission. Almost 20.0% of women treated with antidepressants have a positive screening for bipolar disorder. Therefore, it has been recommended the investigation of depressive and bipolar disorder during prenatal care. Unfortunately, the screening for mood disorders is not a reality in Brazil and many childbearing women remain undiagnosed. The objective of this study is to observe the frequency of MD and the effectiveness of screening scales for routine use by health professionals during prenatal care in high-risk pregnancies.<h4>Methodology/principal findings</h4>This cross-sectional study included 61 childbearing women in their second trimester who were interviewed using the Edinburgh Postnatal Depression Scale (EPDS) and the Mood Disorder Questionnaire (MDQ). The cut-off point was EPDS ≥ 13 and MDQ ≥ 7 and the SCID-5 was the gold standard diagnosis. MD were diagnosed in 24.6% of the high-risk pregnancies. EDPS was positive in 19.7% and the frequency of major depression was 8.2%. 16.4% of the childbearing women were diagnosed with bipolar disorder, while MDQ was positive in 36.1%. 11.5% of the women had EPDS and MDQ positive. EPDS sensitivity was 80.0% and specificity 92.1%, whereas MDQ presented a sensitivity of 70.0% and specificity of 70.6%.<h4>Conclusion/significance</h4>There is a high prevalence of MD in high-risk pregnancies. The routine use of EPDS simultaneously to MDQ during antenatal care is effective and plays an important role in early diagnosis, counselling, and promotion of perinatal mental health.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0261874&type=printable
spellingShingle Fernanda Schier de Fraga
Beatriz Souza Lima Wan-Dall
Gabriel Henrique de Oliveira Garcia
Henrique Pandolfo
Adelyne Mayara Tavares da Silva Sequinel
Pedro Alvin
Eduardo Jonson Serman
Vivian Ferreira do Amaral
Antenatal screening of depressive and manic symptoms in south Brazilian childbearing women: A transversal study in advance of the pandemic scenario.
PLoS ONE
title Antenatal screening of depressive and manic symptoms in south Brazilian childbearing women: A transversal study in advance of the pandemic scenario.
title_full Antenatal screening of depressive and manic symptoms in south Brazilian childbearing women: A transversal study in advance of the pandemic scenario.
title_fullStr Antenatal screening of depressive and manic symptoms in south Brazilian childbearing women: A transversal study in advance of the pandemic scenario.
title_full_unstemmed Antenatal screening of depressive and manic symptoms in south Brazilian childbearing women: A transversal study in advance of the pandemic scenario.
title_short Antenatal screening of depressive and manic symptoms in south Brazilian childbearing women: A transversal study in advance of the pandemic scenario.
title_sort antenatal screening of depressive and manic symptoms in south brazilian childbearing women a transversal study in advance of the pandemic scenario
url https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0261874&type=printable
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