Identification of BTC and KLF15 in Vascular Smooth Muscle Cells as Key Biomarkers for Abdominal Aortic Aneurysm via Machine Learning and In Vitro Experiments

Identification of BTC and KLF15 in Vascular Smooth Muscle Cells as Key Biomarkers for Abdominal Aortic Aneurysm via Machine Learning and In Vitro Experiments

We aimed to identify molecular candidates to serve as diagnostic biomarkers and therapeutic targets for abdominal aortic aneurysm (AAA). We conducted integrative bioinformatics analysis and used machine learning for key genetic screening. Gene expression profiles at the single-cell level were valida...

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Bibliographic Details
Main Authors: Yifei Chen, Honghao Huang, Yuyan Lyu, Yuehong Wang, Jun Pu
Format: Article
Language:English
Published: Compuscript Ltd 2025-03-01
Series:Cardiovascular Innovations and Applications
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2025.0012
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