Taurine, alpha lipoic acid and vitamin B6 ameliorate the reduced developmental competence of immature mouse oocytes exposed to methylglyoxal

Taurine, alpha lipoic acid and vitamin B6 ameliorate the reduced developmental competence of immature mouse oocytes exposed to methylglyoxal

Abstract Advanced glycation end products (AGEs) are the final products of the Maillard reaction, formed through the interaction of carbohydrates and proteins. Reactive dicarbonyl compounds such as methylglyoxal (MGO) serve as precursors for AGEs formation. Elevated levels of MGO/AGEs are observed in...

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Bibliographic Details
Main Authors: Saba Mokhtari, Amir Hossein Mahdavi, Farnoosh Jafarpour, Mohsen Rahimi Andani, Maurizio Dattilo, Mohammad Hossein Nasr-Esfahani
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Series:Scientific Reports
Subjects:
Advanced glycation end products
Alpha lipoic acid
Cumulus oocyte complex
Denuded oocyte
Maturation
Methylglyoxal
Online Access:https://doi.org/10.1038/s41598-024-66785-5
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