A novel patient-derived cutaneous melanoma cell line reveals key features of metastatic melanoma

A novel patient-derived cutaneous melanoma cell line reveals key features of metastatic melanoma

IntroductionCutaneous melanoma (CM) is an aggressive form of skin cancer, with rising incidence and poor prognosis at advanced stages. While early-stage CM typically carries a favorable prognosis, a small subset of patients relapses and progresses to advanced disease, highlighting the need for a dee...

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Main Authors: Ana Tomás, Lúcia Roque, Inês Francisco, Ana Luísa Silva, Hugo Nunes, Emanuel Gouveia, Elisabete Carvalho, Victor Farricha, Cecília Moura, Joaninha Costa Rosa, Pedro Miguel Garrido, Cristina Albuquerque, Patrícia M. Pereira, M. Guadalupe Cabral, Marta Pojo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
cutaneous melanoma
primary cell culture
targeted therapy
immunotherapy
phenotypic plasticity
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1531013/full
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