Evaluation of Vibratory Ball Mill Mixing as an Alternative to Wet Granulation in the Manufacturing of Sodium Naproxen Tablets with Dolomite-Based Formulations

Evaluation of Vibratory Ball Mill Mixing as an Alternative to Wet Granulation in the Manufacturing of Sodium Naproxen Tablets with Dolomite-Based Formulations

The development of robust and scalable tablet manufacturing methods remains a key objective in pharmaceutical technology, especially when dealing with active pharmaceutical ingredients (APIs) and excipients that exhibit suboptimal processing properties. This study evaluated two alternative manufactu...

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Bibliographic Details
Main Authors: Mateusz Przywara, Klaudia Jękot, Wiktoria Jednacz
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Applied Sciences
Subjects:
sodium naproxen
dolomite
direct compression
wet granulation
vibratory mixing
tablet formulation
Online Access:https://www.mdpi.com/2076-3417/15/13/6966
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