A preliminary Study on Anticancer and Antimicrobial Potential of Methanolic Extracts of Verbascum napifolium
Plants are widely used in the treatment of many diseases. This study evaluates for the first time the potential anticancer and antimicrobial activities of methanol extracts of leaves and flower parts of Verbascum napifolium, an endemic species distributed in the flora of Turkey. The antimicrobial a...
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| Format: | Article |
| Language: | English |
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Institute of Economic Develoment and Social Researches
2023-03-01
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| Series: | ISPEC Journal of Agricultural Sciences |
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| Online Access: | https://www.ispecjournal.com/index.php/ispecjas/article/view/424 |
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| author | Aylin TAŞKAYA Burcu ŞAHİN Nur CEYHAN GÜVENSEN Ramazan MAMMADOV |
| author_facet | Aylin TAŞKAYA Burcu ŞAHİN Nur CEYHAN GÜVENSEN Ramazan MAMMADOV |
| author_sort | Aylin TAŞKAYA |
| collection | DOAJ |
| description |
Plants are widely used in the treatment of many diseases. This study evaluates for the first time the potential anticancer and antimicrobial activities of methanol extracts of leaves and flower parts of Verbascum napifolium, an endemic species distributed in the flora of Turkey. The antimicrobial activities were evaluated by the disc diffusion method and by determining the minimal inhibitory concentration (MIC). In all bacteria, flower methanol extract was found to be more sensitive. Escherichia coli was determined to be more sensitive to both extracts compared to all tested bacteria. These results suggest that V napifolium possess potential important anticancer and antimicrobial activities. The anticancer activities the effect of Verbascum napifolium flower and leaf methanol extracts on cell viability in CaCo-2 and L929 cell lines were determined by MTT assay. Flower methanol extract of Verbascum napifolium showed a better anticancer potential than the leaf methanol extract.
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| format | Article |
| id | doaj-art-fa6fe1073b944fdcb9fb6d5ea5263c7a |
| institution | DOAJ |
| issn | 2717-7238 |
| language | English |
| publishDate | 2023-03-01 |
| publisher | Institute of Economic Develoment and Social Researches |
| record_format | Article |
| series | ISPEC Journal of Agricultural Sciences |
| spelling | doaj-art-fa6fe1073b944fdcb9fb6d5ea5263c7a2025-08-20T02:55:48ZengInstitute of Economic Develoment and Social ResearchesISPEC Journal of Agricultural Sciences2717-72382023-03-017110.5281/zenodo.7749361A preliminary Study on Anticancer and Antimicrobial Potential of Methanolic Extracts of Verbascum napifoliumAylin TAŞKAYA0Burcu ŞAHİN1Nur CEYHAN GÜVENSEN2Ramazan MAMMADOV3Muğla Sıtkı Koçman University, Faculty of Sciences, Department of Biology, MuğlaMuğla Sıtkı Koçman University, Faculty of Sciences, Department of Molecular Biology and Genetics, MuğlaEge University, Tire Kutsan Vocational School, Food Technology Program, İzmirMuğla Sıtkı Koçman University, Faculty of Sciences, Department of Molecular Biology and Genetics, Muğla Plants are widely used in the treatment of many diseases. This study evaluates for the first time the potential anticancer and antimicrobial activities of methanol extracts of leaves and flower parts of Verbascum napifolium, an endemic species distributed in the flora of Turkey. The antimicrobial activities were evaluated by the disc diffusion method and by determining the minimal inhibitory concentration (MIC). In all bacteria, flower methanol extract was found to be more sensitive. Escherichia coli was determined to be more sensitive to both extracts compared to all tested bacteria. These results suggest that V napifolium possess potential important anticancer and antimicrobial activities. The anticancer activities the effect of Verbascum napifolium flower and leaf methanol extracts on cell viability in CaCo-2 and L929 cell lines were determined by MTT assay. Flower methanol extract of Verbascum napifolium showed a better anticancer potential than the leaf methanol extract. https://www.ispecjournal.com/index.php/ispecjas/article/view/424Verbascum napifoliumanticancer activityantimicrobial activityCaCo-2human cancer colon |
| spellingShingle | Aylin TAŞKAYA Burcu ŞAHİN Nur CEYHAN GÜVENSEN Ramazan MAMMADOV A preliminary Study on Anticancer and Antimicrobial Potential of Methanolic Extracts of Verbascum napifolium ISPEC Journal of Agricultural Sciences Verbascum napifolium anticancer activity antimicrobial activity CaCo-2 human cancer colon |
| title | A preliminary Study on Anticancer and Antimicrobial Potential of Methanolic Extracts of Verbascum napifolium |
| title_full | A preliminary Study on Anticancer and Antimicrobial Potential of Methanolic Extracts of Verbascum napifolium |
| title_fullStr | A preliminary Study on Anticancer and Antimicrobial Potential of Methanolic Extracts of Verbascum napifolium |
| title_full_unstemmed | A preliminary Study on Anticancer and Antimicrobial Potential of Methanolic Extracts of Verbascum napifolium |
| title_short | A preliminary Study on Anticancer and Antimicrobial Potential of Methanolic Extracts of Verbascum napifolium |
| title_sort | preliminary study on anticancer and antimicrobial potential of methanolic extracts of verbascum napifolium |
| topic | Verbascum napifolium anticancer activity antimicrobial activity CaCo-2 human cancer colon |
| url | https://www.ispecjournal.com/index.php/ispecjas/article/view/424 |
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