Effect of focused ultrasound neuromodulation of the superior mesenteric plexus on insulin sensitivity and post-operative hyperglycemia in a swine model of surgical stress

Effect of focused ultrasound neuromodulation of the superior mesenteric plexus on insulin sensitivity and post-operative hyperglycemia in a swine model of surgical stress

Abstract Metabolic stress during major surgery increases insulin resistance and causes post-operative hyperglycemia (POHG), which may in turn contribute to post-operative morbidity and mortality. Intensive insulin therapy for POHG is often ineffective and may even worsen patient outcomes. Non-invasi...

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Bibliographic Details
Main Authors: Weiguo Song, Khaled Qanud, Dane A. Thompson, Jared M. Huston, Stavros Zanos
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Bioelectronic Medicine
Subjects:
Focused ultrasound stimulation
Superior mesenteric plexus
Neuromodulation
Post-operative hyperglycemia
Online Access:https://doi.org/10.1186/s42234-025-00176-7
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