Effect of rheumatoid arthritis activity on corneal densitometry, curvature, thickness, and lens densitometry

Purpose To evaluate the effect of rheumatoid arthritis (RA) activity on the corneal densitometry, corneal curvature (CC), central corneal thickness (CCT), and lens densitometry and compare these parameters with healthy control patients. Patients and methods Prospective cross–sectional-controlled stu...

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Main Authors: Mohamed S.E. Mahmoud, Ahmed Hamed, Mohamed E. Abdullah, Mohamed T. Moustafa, Doaa ElFadaly
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-04-01
Series:Journal of the Egyptian Ophthalmological Society
Subjects:
Online Access:https://journals.lww.com/10.4103/ejos.ejos_58_24
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author Mohamed S.E. Mahmoud
Ahmed Hamed
Mohamed E. Abdullah
Mohamed T. Moustafa
Doaa ElFadaly
author_facet Mohamed S.E. Mahmoud
Ahmed Hamed
Mohamed E. Abdullah
Mohamed T. Moustafa
Doaa ElFadaly
author_sort Mohamed S.E. Mahmoud
collection DOAJ
description Purpose To evaluate the effect of rheumatoid arthritis (RA) activity on the corneal densitometry, corneal curvature (CC), central corneal thickness (CCT), and lens densitometry and compare these parameters with healthy control patients. Patients and methods Prospective cross–sectional-controlled study on RA patients who were divided into 2 groups, each group with 120 eyes of 60 patients; group 1 of RA patients in the remission state and group 2 of RA patients in the active state. Control group 3 of 120 eyes of healthy controls. Scheimpflug imaging was used to measure corneal densitometry, CC, CCT, and lens densitometry. Results Compared with control group, a higher density was found in corneal densitometry in both RA groups. The density was mainly higher in the 0–2 mm and 2–6 mm radial zones of the anterior layer and the 10–12 mm zone of both the central and posterior layers with no significant difference between groups 1 and 2 of RA patients. Regarding the CCT, there was a significant reduction in the CCT between both RA groups compared with the control group, with no difference between groups 1 and 2. No significant difference was found in CC and lens densitometry between RA and control groups. Conclusion RA patients had higher corneal densitometry than healthy patients with no affection of RA activity on corneal and lens densitometry.
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spelling doaj-art-fa5b6e4cef0a4b979176f9d08362104e2025-08-20T02:16:21ZengWolters Kluwer Medknow PublicationsJournal of the Egyptian Ophthalmological Society2090-06862025-04-01118211412010.4103/ejos.ejos_58_24Effect of rheumatoid arthritis activity on corneal densitometry, curvature, thickness, and lens densitometryMohamed S.E. MahmoudAhmed HamedMohamed E. AbdullahMohamed T. MoustafaDoaa ElFadalyPurpose To evaluate the effect of rheumatoid arthritis (RA) activity on the corneal densitometry, corneal curvature (CC), central corneal thickness (CCT), and lens densitometry and compare these parameters with healthy control patients. Patients and methods Prospective cross–sectional-controlled study on RA patients who were divided into 2 groups, each group with 120 eyes of 60 patients; group 1 of RA patients in the remission state and group 2 of RA patients in the active state. Control group 3 of 120 eyes of healthy controls. Scheimpflug imaging was used to measure corneal densitometry, CC, CCT, and lens densitometry. Results Compared with control group, a higher density was found in corneal densitometry in both RA groups. The density was mainly higher in the 0–2 mm and 2–6 mm radial zones of the anterior layer and the 10–12 mm zone of both the central and posterior layers with no significant difference between groups 1 and 2 of RA patients. Regarding the CCT, there was a significant reduction in the CCT between both RA groups compared with the control group, with no difference between groups 1 and 2. No significant difference was found in CC and lens densitometry between RA and control groups. Conclusion RA patients had higher corneal densitometry than healthy patients with no affection of RA activity on corneal and lens densitometry.https://journals.lww.com/10.4103/ejos.ejos_58_24corneal densitometrylens densitometryrheumatoid arthritis
spellingShingle Mohamed S.E. Mahmoud
Ahmed Hamed
Mohamed E. Abdullah
Mohamed T. Moustafa
Doaa ElFadaly
Effect of rheumatoid arthritis activity on corneal densitometry, curvature, thickness, and lens densitometry
Journal of the Egyptian Ophthalmological Society
corneal densitometry
lens densitometry
rheumatoid arthritis
title Effect of rheumatoid arthritis activity on corneal densitometry, curvature, thickness, and lens densitometry
title_full Effect of rheumatoid arthritis activity on corneal densitometry, curvature, thickness, and lens densitometry
title_fullStr Effect of rheumatoid arthritis activity on corneal densitometry, curvature, thickness, and lens densitometry
title_full_unstemmed Effect of rheumatoid arthritis activity on corneal densitometry, curvature, thickness, and lens densitometry
title_short Effect of rheumatoid arthritis activity on corneal densitometry, curvature, thickness, and lens densitometry
title_sort effect of rheumatoid arthritis activity on corneal densitometry curvature thickness and lens densitometry
topic corneal densitometry
lens densitometry
rheumatoid arthritis
url https://journals.lww.com/10.4103/ejos.ejos_58_24
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AT mohamedeabdullah effectofrheumatoidarthritisactivityoncornealdensitometrycurvaturethicknessandlensdensitometry
AT mohamedtmoustafa effectofrheumatoidarthritisactivityoncornealdensitometrycurvaturethicknessandlensdensitometry
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