Retroperitoneal fibrous tumor recurring as lung metastases after 10 years: a case report

Abstract Background Solitary fibrous tumor (SFT) is a relatively rare mesenchymal tumor that mainly affects adults. Its prognosis is good after curative resection, but distant recurrences after 10 years or longer have been reported. Recurrent SFT usually arises as a local lesion; distant metastasis...

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Main Authors: Kozue Matsuishi, Kojiro Eto, Atsushi Morito, Hirokazu Hamasaki, Keisuke Morita, Satoshi Ikeshima, Kei Horino, Shinya Shimada, Hideo Baba
Format: Article
Language:English
Published: Japan Surgical Society 2021-05-01
Series:Surgical Case Reports
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Online Access:https://doi.org/10.1186/s40792-021-01209-4
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author Kozue Matsuishi
Kojiro Eto
Atsushi Morito
Hirokazu Hamasaki
Keisuke Morita
Satoshi Ikeshima
Kei Horino
Shinya Shimada
Hideo Baba
author_facet Kozue Matsuishi
Kojiro Eto
Atsushi Morito
Hirokazu Hamasaki
Keisuke Morita
Satoshi Ikeshima
Kei Horino
Shinya Shimada
Hideo Baba
author_sort Kozue Matsuishi
collection DOAJ
description Abstract Background Solitary fibrous tumor (SFT) is a relatively rare mesenchymal tumor that mainly affects adults. Its prognosis is good after curative resection, but distant recurrences after 10 years or longer have been reported. Recurrent SFT usually arises as a local lesion; distant metastasis is rarely reported. Here, we report lung metastases that recurred a decade after excising a retroperitoneal primary SFT. Case presentation A 44-year-old woman had an SFT resected from her right retroperitoneum at our hospital. Ten years later, at age 54, she underwent a lung resection after CT showed three suspected metastases in her left lung. All three were histologically diagnosed as lung metastases from the retroperitoneal SFT. However, whereas the primary SFT had 1–2 mitotic cells/10 high power fields (HPF), the metastatic lesion increased malignancy, at 50/10 HPF. Conclusion Patients who have had resected SFTs should be carefully followed up, as malignancy may change in distant metastasis, as in this case.
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series Surgical Case Reports
spelling doaj-art-fa5a169b73e547c9a15ff2c0e515fdc92025-08-20T02:49:16ZengJapan Surgical SocietySurgical Case Reports2198-77932021-05-01711510.1186/s40792-021-01209-4Retroperitoneal fibrous tumor recurring as lung metastases after 10 years: a case reportKozue Matsuishi0Kojiro Eto1Atsushi Morito2Hirokazu Hamasaki3Keisuke Morita4Satoshi Ikeshima5Kei Horino6Shinya Shimada7Hideo Baba8Department of Surgery, Japan Community Health Care Organization Kumamoto General HospitalDepartment of Surgery, Japan Community Health Care Organization Kumamoto General HospitalDepartment of Surgery, Japan Community Health Care Organization Kumamoto General HospitalDepartment of Surgery, Japan Community Health Care Organization Kumamoto General HospitalDepartment of Surgery, Japan Community Health Care Organization Kumamoto General HospitalDepartment of Surgery, Japan Community Health Care Organization Kumamoto General HospitalDepartment of Surgery, Japan Community Health Care Organization Kumamoto General HospitalDepartment of Surgery, Japan Community Health Care Organization Kumamoto General HospitalDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto UniversityAbstract Background Solitary fibrous tumor (SFT) is a relatively rare mesenchymal tumor that mainly affects adults. Its prognosis is good after curative resection, but distant recurrences after 10 years or longer have been reported. Recurrent SFT usually arises as a local lesion; distant metastasis is rarely reported. Here, we report lung metastases that recurred a decade after excising a retroperitoneal primary SFT. Case presentation A 44-year-old woman had an SFT resected from her right retroperitoneum at our hospital. Ten years later, at age 54, she underwent a lung resection after CT showed three suspected metastases in her left lung. All three were histologically diagnosed as lung metastases from the retroperitoneal SFT. However, whereas the primary SFT had 1–2 mitotic cells/10 high power fields (HPF), the metastatic lesion increased malignancy, at 50/10 HPF. Conclusion Patients who have had resected SFTs should be carefully followed up, as malignancy may change in distant metastasis, as in this case.https://doi.org/10.1186/s40792-021-01209-4Malignant solitary fibrous tumorRetroperitoneumHistopathology
spellingShingle Kozue Matsuishi
Kojiro Eto
Atsushi Morito
Hirokazu Hamasaki
Keisuke Morita
Satoshi Ikeshima
Kei Horino
Shinya Shimada
Hideo Baba
Retroperitoneal fibrous tumor recurring as lung metastases after 10 years: a case report
Surgical Case Reports
Malignant solitary fibrous tumor
Retroperitoneum
Histopathology
title Retroperitoneal fibrous tumor recurring as lung metastases after 10 years: a case report
title_full Retroperitoneal fibrous tumor recurring as lung metastases after 10 years: a case report
title_fullStr Retroperitoneal fibrous tumor recurring as lung metastases after 10 years: a case report
title_full_unstemmed Retroperitoneal fibrous tumor recurring as lung metastases after 10 years: a case report
title_short Retroperitoneal fibrous tumor recurring as lung metastases after 10 years: a case report
title_sort retroperitoneal fibrous tumor recurring as lung metastases after 10 years a case report
topic Malignant solitary fibrous tumor
Retroperitoneum
Histopathology
url https://doi.org/10.1186/s40792-021-01209-4
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