Bilateral inverted papilloma: Case report and literature review
Inverted papilloma is a rare, benign epithelial tumor of the nasal and sinus cavities with an unclear etiology. It usually presents as unilateral nasal obstruction. Diagnosis is histological, and treatment is primarily surgical. We describe a 72-year-old patient with persistent bilateral nasal obstr...
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Elsevier
2025-03-01
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author | Mohammed Amine Rabhi Achraf Amine Sbai Drissia Benfadil Azzedine Lachkar Adil Abdenbi Tsen Fahd Elayoubi |
author_facet | Mohammed Amine Rabhi Achraf Amine Sbai Drissia Benfadil Azzedine Lachkar Adil Abdenbi Tsen Fahd Elayoubi |
author_sort | Mohammed Amine Rabhi |
collection | DOAJ |
description | Inverted papilloma is a rare, benign epithelial tumor of the nasal and sinus cavities with an unclear etiology. It usually presents as unilateral nasal obstruction. Diagnosis is histological, and treatment is primarily surgical. We describe a 72-year-old patient with persistent bilateral nasal obstruction. Examination revealed a greyish-pink, multi-lobed mass in both nasal cavities pressing on the hard palate. Imaging (CT and MRI) showed a cerebriform mass extending through the nasal cavities and into the nasopharynx, causing bone destruction without intracranial or intra-orbital spread. Histopathology confirmed a bilateral inverted papilloma without malignancy. Inverted papilloma comprises less than 4% of primary nasal tumors. It is noted for high local aggressiveness, frequent recurrences, and potential association with squamous cell carcinoma. Imaging (CT and MRI) aids in staging and selecting the surgical approach—endoscopic, external, or combined. Close surveillance via endoscopy and imaging is crucial. Although benign, inverted papilloma is highly invasive. Accurate diagnosis and complete surgical removal are essential to minimize recurrence risk. |
format | Article |
id | doaj-art-fa5804794a2243e2995096ead7dac12b |
institution | Kabale University |
issn | 1930-0433 |
language | English |
publishDate | 2025-03-01 |
publisher | Elsevier |
record_format | Article |
series | Radiology Case Reports |
spelling | doaj-art-fa5804794a2243e2995096ead7dac12b2025-01-18T05:03:54ZengElsevierRadiology Case Reports1930-04332025-03-0120314991503Bilateral inverted papilloma: Case report and literature reviewMohammed Amine Rabhi0Achraf Amine Sbai1Drissia Benfadil2Azzedine Lachkar3Adil Abdenbi Tsen4Fahd Elayoubi5Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco; Department of Ear Nose and Throat, Mohammed VI University Hospital Mohammed First University, Oujda, Morocco; Mohammed First University, Faculty of Medicine and Pharmacy, LAMCESM, Oujda, Morocco; Corresponding author.Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco; Department of Ear Nose and Throat, Mohammed VI University Hospital Mohammed First University, Oujda, Morocco; Mohammed First University, Faculty of Medicine and Pharmacy, LAMCESM, Oujda, MoroccoFaculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco; Department of Ear Nose and Throat, Mohammed VI University Hospital Mohammed First University, Oujda, Morocco; Mohammed First University, Faculty of Medicine and Pharmacy, LAMCESM, Oujda, MoroccoFaculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco; Department of Ear Nose and Throat, Mohammed VI University Hospital Mohammed First University, Oujda, Morocco; Mohammed First University, Faculty of Medicine and Pharmacy, LAMCESM, Oujda, MoroccoFaculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco; Mohammed First University, Faculty of Medicine and Pharmacy, LAMCESM, Oujda, MoroccoFaculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco; Department of Ear Nose and Throat, Mohammed VI University Hospital Mohammed First University, Oujda, Morocco; Mohammed First University, Faculty of Medicine and Pharmacy, LAMCESM, Oujda, MoroccoInverted papilloma is a rare, benign epithelial tumor of the nasal and sinus cavities with an unclear etiology. It usually presents as unilateral nasal obstruction. Diagnosis is histological, and treatment is primarily surgical. We describe a 72-year-old patient with persistent bilateral nasal obstruction. Examination revealed a greyish-pink, multi-lobed mass in both nasal cavities pressing on the hard palate. Imaging (CT and MRI) showed a cerebriform mass extending through the nasal cavities and into the nasopharynx, causing bone destruction without intracranial or intra-orbital spread. Histopathology confirmed a bilateral inverted papilloma without malignancy. Inverted papilloma comprises less than 4% of primary nasal tumors. It is noted for high local aggressiveness, frequent recurrences, and potential association with squamous cell carcinoma. Imaging (CT and MRI) aids in staging and selecting the surgical approach—endoscopic, external, or combined. Close surveillance via endoscopy and imaging is crucial. Although benign, inverted papilloma is highly invasive. Accurate diagnosis and complete surgical removal are essential to minimize recurrence risk.http://www.sciencedirect.com/science/article/pii/S1930043324013153Inverted papillomaNasal obstructionBenign nasal tumorParanasal sinus |
spellingShingle | Mohammed Amine Rabhi Achraf Amine Sbai Drissia Benfadil Azzedine Lachkar Adil Abdenbi Tsen Fahd Elayoubi Bilateral inverted papilloma: Case report and literature review Radiology Case Reports Inverted papilloma Nasal obstruction Benign nasal tumor Paranasal sinus |
title | Bilateral inverted papilloma: Case report and literature review |
title_full | Bilateral inverted papilloma: Case report and literature review |
title_fullStr | Bilateral inverted papilloma: Case report and literature review |
title_full_unstemmed | Bilateral inverted papilloma: Case report and literature review |
title_short | Bilateral inverted papilloma: Case report and literature review |
title_sort | bilateral inverted papilloma case report and literature review |
topic | Inverted papilloma Nasal obstruction Benign nasal tumor Paranasal sinus |
url | http://www.sciencedirect.com/science/article/pii/S1930043324013153 |
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