Bilateral inverted papilloma: Case report and literature review

Inverted papilloma is a rare, benign epithelial tumor of the nasal and sinus cavities with an unclear etiology. It usually presents as unilateral nasal obstruction. Diagnosis is histological, and treatment is primarily surgical. We describe a 72-year-old patient with persistent bilateral nasal obstr...

Full description

Saved in:
Bibliographic Details
Main Authors: Mohammed Amine Rabhi, Achraf Amine Sbai, Drissia Benfadil, Azzedine Lachkar, Adil Abdenbi Tsen, Fahd Elayoubi
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Radiology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1930043324013153
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832595860191444992
author Mohammed Amine Rabhi
Achraf Amine Sbai
Drissia Benfadil
Azzedine Lachkar
Adil Abdenbi Tsen
Fahd Elayoubi
author_facet Mohammed Amine Rabhi
Achraf Amine Sbai
Drissia Benfadil
Azzedine Lachkar
Adil Abdenbi Tsen
Fahd Elayoubi
author_sort Mohammed Amine Rabhi
collection DOAJ
description Inverted papilloma is a rare, benign epithelial tumor of the nasal and sinus cavities with an unclear etiology. It usually presents as unilateral nasal obstruction. Diagnosis is histological, and treatment is primarily surgical. We describe a 72-year-old patient with persistent bilateral nasal obstruction. Examination revealed a greyish-pink, multi-lobed mass in both nasal cavities pressing on the hard palate. Imaging (CT and MRI) showed a cerebriform mass extending through the nasal cavities and into the nasopharynx, causing bone destruction without intracranial or intra-orbital spread. Histopathology confirmed a bilateral inverted papilloma without malignancy. Inverted papilloma comprises less than 4% of primary nasal tumors. It is noted for high local aggressiveness, frequent recurrences, and potential association with squamous cell carcinoma. Imaging (CT and MRI) aids in staging and selecting the surgical approach—endoscopic, external, or combined. Close surveillance via endoscopy and imaging is crucial. Although benign, inverted papilloma is highly invasive. Accurate diagnosis and complete surgical removal are essential to minimize recurrence risk.
format Article
id doaj-art-fa5804794a2243e2995096ead7dac12b
institution Kabale University
issn 1930-0433
language English
publishDate 2025-03-01
publisher Elsevier
record_format Article
series Radiology Case Reports
spelling doaj-art-fa5804794a2243e2995096ead7dac12b2025-01-18T05:03:54ZengElsevierRadiology Case Reports1930-04332025-03-0120314991503Bilateral inverted papilloma: Case report and literature reviewMohammed Amine Rabhi0Achraf Amine Sbai1Drissia Benfadil2Azzedine Lachkar3Adil Abdenbi Tsen4Fahd Elayoubi5Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco; Department of Ear Nose and Throat, Mohammed VI University Hospital Mohammed First University, Oujda, Morocco; Mohammed First University, Faculty of Medicine and Pharmacy, LAMCESM, Oujda, Morocco; Corresponding author.Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco; Department of Ear Nose and Throat, Mohammed VI University Hospital Mohammed First University, Oujda, Morocco; Mohammed First University, Faculty of Medicine and Pharmacy, LAMCESM, Oujda, MoroccoFaculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco; Department of Ear Nose and Throat, Mohammed VI University Hospital Mohammed First University, Oujda, Morocco; Mohammed First University, Faculty of Medicine and Pharmacy, LAMCESM, Oujda, MoroccoFaculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco; Department of Ear Nose and Throat, Mohammed VI University Hospital Mohammed First University, Oujda, Morocco; Mohammed First University, Faculty of Medicine and Pharmacy, LAMCESM, Oujda, MoroccoFaculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco; Mohammed First University, Faculty of Medicine and Pharmacy, LAMCESM, Oujda, MoroccoFaculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco; Department of Ear Nose and Throat, Mohammed VI University Hospital Mohammed First University, Oujda, Morocco; Mohammed First University, Faculty of Medicine and Pharmacy, LAMCESM, Oujda, MoroccoInverted papilloma is a rare, benign epithelial tumor of the nasal and sinus cavities with an unclear etiology. It usually presents as unilateral nasal obstruction. Diagnosis is histological, and treatment is primarily surgical. We describe a 72-year-old patient with persistent bilateral nasal obstruction. Examination revealed a greyish-pink, multi-lobed mass in both nasal cavities pressing on the hard palate. Imaging (CT and MRI) showed a cerebriform mass extending through the nasal cavities and into the nasopharynx, causing bone destruction without intracranial or intra-orbital spread. Histopathology confirmed a bilateral inverted papilloma without malignancy. Inverted papilloma comprises less than 4% of primary nasal tumors. It is noted for high local aggressiveness, frequent recurrences, and potential association with squamous cell carcinoma. Imaging (CT and MRI) aids in staging and selecting the surgical approach—endoscopic, external, or combined. Close surveillance via endoscopy and imaging is crucial. Although benign, inverted papilloma is highly invasive. Accurate diagnosis and complete surgical removal are essential to minimize recurrence risk.http://www.sciencedirect.com/science/article/pii/S1930043324013153Inverted papillomaNasal obstructionBenign nasal tumorParanasal sinus
spellingShingle Mohammed Amine Rabhi
Achraf Amine Sbai
Drissia Benfadil
Azzedine Lachkar
Adil Abdenbi Tsen
Fahd Elayoubi
Bilateral inverted papilloma: Case report and literature review
Radiology Case Reports
Inverted papilloma
Nasal obstruction
Benign nasal tumor
Paranasal sinus
title Bilateral inverted papilloma: Case report and literature review
title_full Bilateral inverted papilloma: Case report and literature review
title_fullStr Bilateral inverted papilloma: Case report and literature review
title_full_unstemmed Bilateral inverted papilloma: Case report and literature review
title_short Bilateral inverted papilloma: Case report and literature review
title_sort bilateral inverted papilloma case report and literature review
topic Inverted papilloma
Nasal obstruction
Benign nasal tumor
Paranasal sinus
url http://www.sciencedirect.com/science/article/pii/S1930043324013153
work_keys_str_mv AT mohammedaminerabhi bilateralinvertedpapillomacasereportandliteraturereview
AT achrafaminesbai bilateralinvertedpapillomacasereportandliteraturereview
AT drissiabenfadil bilateralinvertedpapillomacasereportandliteraturereview
AT azzedinelachkar bilateralinvertedpapillomacasereportandliteraturereview
AT adilabdenbitsen bilateralinvertedpapillomacasereportandliteraturereview
AT fahdelayoubi bilateralinvertedpapillomacasereportandliteraturereview