Blocking REDD1/TXNIP Complex Ameliorates HG-Induced Renal Tubular Epithelial Cell Apoptosis and EMT through Repressing Oxidative Stress
Diabetic nephropathy (DN) has become the most common secondary kidney disease causing end-stage renal disease (ESRD). Nevertheless, the underlying mechanisms responsible for DN remain largely unknown. Regulated in development and DNA damage response 1 (REDD1) is a prooxidative molecule known to cont...
Saved in:
Main Authors: | Lin Mu, Nan Chen, Yakun Chen, Zhifen Yang, Huandi Zhou, Shan Song, Yonghong Shi |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2022-01-01
|
Series: | International Journal of Endocrinology |
Online Access: | http://dx.doi.org/10.1155/2022/6073911 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
CXC chemokine receptor 7 ameliorates renal fibrosis by inhibiting β-catenin signaling and epithelial-to-mesenchymal transition in tubular epithelial cells
by: Ping Meng, et al.
Published: (2024-12-01) -
Ethanol Extracts of Solanum lyratum Thunb Regulate Ovarian Cancer Cell Proliferation, Apoptosis, and Epithelial-to-Mesenchymal Transition (EMT) via the ROS-Mediated p53 Pathway
by: Chen Zhang, et al.
Published: (2021-01-01) -
REDD1 mediates HDM-induced nuclear-cytoplasmic translocation and release of IL-33 in airway epithelial cells by downregulating Nrf2
by: Tian Luo, et al.
Published: (2025-02-01) -
Lessons From Early REDD+ Experiences in the Philippines
by: Rodel D. Lasco, et al.
Published: (2013-01-01) -
Participatory Forest Carbon Assessment and REDD+: Learning from Tanzania
by: Kusaga Mukama, et al.
Published: (2012-01-01)