Induced mesenchymal stem cells generated from periodontal ligament fibroblast for regenerative therapy

Induced mesenchymal stem cells generated from periodontal ligament fibroblast for regenerative therapy

Bone fractures and bone loss represent significant global health challenges, with their incidence rising due to an aging population. Despite autologous bone grafts remain the gold standard for treatment, challenges such as limited bone availability, immune reactions, and the risk of infectious disea...

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Bibliographic Details
Main Authors: Hemanathan Vembuli, Sheeja Rajasingh, Patrick Nabholz, Jefferson Guenther, Brian R. Morrow, Margaret M. Taylor, Marziyeh Aghazadeh, Vinoth Sigamani, Johnson Rajasingh
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Experimental Biology and Medicine
Subjects:
mesenchymal stem cells
induced pluripotent stem cells
differentiation
osteocytes
regenerative therapy
Online Access:https://www.ebm-journal.org/articles/10.3389/ebm.2025.10342/full
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