Ischemic Stroke in an HIV Positive Patient: An Initial Presentation of Neurosyphilis

Ischemic stroke occurring in patients with human immunodeficiency virus (HIV) needs to be approached with a vast differential diagnosis in mind. We report a case of middle-aged male patient with immune reconstituted HIV on therapy without known cardiovascular risk factors who had a right middle cere...

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Main Authors: Kalimullah Jan, Rebecca Hoe Hui Min, Tan Seow Yen, Shekhawat Ravindra Singh
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2018/2410154
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author Kalimullah Jan
Rebecca Hoe Hui Min
Tan Seow Yen
Shekhawat Ravindra Singh
author_facet Kalimullah Jan
Rebecca Hoe Hui Min
Tan Seow Yen
Shekhawat Ravindra Singh
author_sort Kalimullah Jan
collection DOAJ
description Ischemic stroke occurring in patients with human immunodeficiency virus (HIV) needs to be approached with a vast differential diagnosis in mind. We report a case of middle-aged male patient with immune reconstituted HIV on therapy without known cardiovascular risk factors who had a right middle cerebral artery territory infarct. After a thorough evaluation, he received a final diagnosis of neurosyphilis-associated vasculitis leading to stroke. He recovered without any neurological deficits following treatment with intravenous benzylpenicillin. Neurosyphilis is an easily diagnosed and treatable cause of a stroke that can be an initial presentation of neurosyphilis but requires a high index of suspicion.
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institution DOAJ
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publishDate 2018-01-01
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series Case Reports in Neurological Medicine
spelling doaj-art-fa459e37b9054abf9d2c5e22a83eb2c02025-08-20T03:20:02ZengWileyCase Reports in Neurological Medicine2090-66682090-66762018-01-01201810.1155/2018/24101542410154Ischemic Stroke in an HIV Positive Patient: An Initial Presentation of NeurosyphilisKalimullah Jan0Rebecca Hoe Hui Min1Tan Seow Yen2Shekhawat Ravindra Singh3Department of Medicine, Changi General Hospital, SingaporeDepartment of Medicine, Changi General Hospital, SingaporeDepartment of Infectious Diseases, Changi General Hospital, SingaporeDepartment of Neurology, Changi General Hospital, SingaporeIschemic stroke occurring in patients with human immunodeficiency virus (HIV) needs to be approached with a vast differential diagnosis in mind. We report a case of middle-aged male patient with immune reconstituted HIV on therapy without known cardiovascular risk factors who had a right middle cerebral artery territory infarct. After a thorough evaluation, he received a final diagnosis of neurosyphilis-associated vasculitis leading to stroke. He recovered without any neurological deficits following treatment with intravenous benzylpenicillin. Neurosyphilis is an easily diagnosed and treatable cause of a stroke that can be an initial presentation of neurosyphilis but requires a high index of suspicion.http://dx.doi.org/10.1155/2018/2410154
spellingShingle Kalimullah Jan
Rebecca Hoe Hui Min
Tan Seow Yen
Shekhawat Ravindra Singh
Ischemic Stroke in an HIV Positive Patient: An Initial Presentation of Neurosyphilis
Case Reports in Neurological Medicine
title Ischemic Stroke in an HIV Positive Patient: An Initial Presentation of Neurosyphilis
title_full Ischemic Stroke in an HIV Positive Patient: An Initial Presentation of Neurosyphilis
title_fullStr Ischemic Stroke in an HIV Positive Patient: An Initial Presentation of Neurosyphilis
title_full_unstemmed Ischemic Stroke in an HIV Positive Patient: An Initial Presentation of Neurosyphilis
title_short Ischemic Stroke in an HIV Positive Patient: An Initial Presentation of Neurosyphilis
title_sort ischemic stroke in an hiv positive patient an initial presentation of neurosyphilis
url http://dx.doi.org/10.1155/2018/2410154
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AT rebeccahoehuimin ischemicstrokeinanhivpositivepatientaninitialpresentationofneurosyphilis
AT tanseowyen ischemicstrokeinanhivpositivepatientaninitialpresentationofneurosyphilis
AT shekhawatravindrasingh ischemicstrokeinanhivpositivepatientaninitialpresentationofneurosyphilis