Norfloxacin inhibited the growth, development and reproduction of Grapholita molesta by reducing the abundance of Enterobacteriaceae bacteria in the guts of larva and ovaries of female moth
While antibiotics are occasionally used in orchard bacterial disease management, their ecological impacts remain understudied. This investigation reveals significant sublethal effects of norfloxacin on the key fruit tree pest Grapholita molesta (oriental fruit moth). Our results showed that the anti...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-06-01
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| Series: | Ecotoxicology and Environmental Safety |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S014765132500658X |
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| author | Shaokai Liu Xueying Liu Donghan Wang Junjie Li Yanshen Fu Chunyang Guo Huilin Tang Junheng Gao Xiangqun Yuan Yiping Li |
| author_facet | Shaokai Liu Xueying Liu Donghan Wang Junjie Li Yanshen Fu Chunyang Guo Huilin Tang Junheng Gao Xiangqun Yuan Yiping Li |
| author_sort | Shaokai Liu |
| collection | DOAJ |
| description | While antibiotics are occasionally used in orchard bacterial disease management, their ecological impacts remain understudied. This investigation reveals significant sublethal effects of norfloxacin on the key fruit tree pest Grapholita molesta (oriental fruit moth). Our results showed that the antibiotic norfloxacin induced multiple developmental alterations by reducing the abundance of Enterobacteriaceae bacteria in the larval guts and adult ovaries: larval stage prolongation (+8.64 %), reduced pupal weight (-6.95 %), shortened adult period (-9.55 %), and impaired female fecundity with 24.77 % lower egg production and 16.57 % reduced egg hatchability. Our findings demonstrate that optimized antibiotic applications could simultaneously manage bacterial pathogens and suppress pest populations, providing dual agricultural benefits. This study proposes a novel integrated approach for orchard management through targeted antibiotic utilization. |
| format | Article |
| id | doaj-art-fa44fc044cb541eaac48d7fa6291701a |
| institution | Kabale University |
| issn | 0147-6513 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Ecotoxicology and Environmental Safety |
| spelling | doaj-art-fa44fc044cb541eaac48d7fa6291701a2025-08-20T03:53:53ZengElsevierEcotoxicology and Environmental Safety0147-65132025-06-0129811832210.1016/j.ecoenv.2025.118322Norfloxacin inhibited the growth, development and reproduction of Grapholita molesta by reducing the abundance of Enterobacteriaceae bacteria in the guts of larva and ovaries of female mothShaokai Liu0Xueying Liu1Donghan Wang2Junjie Li3Yanshen Fu4Chunyang Guo5Huilin Tang6Junheng Gao7Xiangqun Yuan8Yiping Li9Key Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, Key Laboratory of Integrated Pest Management on Crops in Northwestern Loess Plateau of Ministry of Agriculture and Rural Affairs, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, ChinaKey Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, Key Laboratory of Integrated Pest Management on Crops in Northwestern Loess Plateau of Ministry of Agriculture and Rural Affairs, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, ChinaKey Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, Key Laboratory of Integrated Pest Management on Crops in Northwestern Loess Plateau of Ministry of Agriculture and Rural Affairs, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, ChinaKey Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, Key Laboratory of Integrated Pest Management on Crops in Northwestern Loess Plateau of Ministry of Agriculture and Rural Affairs, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, ChinaKey Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, Key Laboratory of Integrated Pest Management on Crops in Northwestern Loess Plateau of Ministry of Agriculture and Rural Affairs, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, ChinaKey Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, Key Laboratory of Integrated Pest Management on Crops in Northwestern Loess Plateau of Ministry of Agriculture and Rural Affairs, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, ChinaKey Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, Key Laboratory of Integrated Pest Management on Crops in Northwestern Loess Plateau of Ministry of Agriculture and Rural Affairs, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, ChinaKey Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, Key Laboratory of Integrated Pest Management on Crops in Northwestern Loess Plateau of Ministry of Agriculture and Rural Affairs, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, ChinaKey Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, Key Laboratory of Integrated Pest Management on Crops in Northwestern Loess Plateau of Ministry of Agriculture and Rural Affairs, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, ChinaCorresponding author.; Key Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, Key Laboratory of Integrated Pest Management on Crops in Northwestern Loess Plateau of Ministry of Agriculture and Rural Affairs, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, ChinaWhile antibiotics are occasionally used in orchard bacterial disease management, their ecological impacts remain understudied. This investigation reveals significant sublethal effects of norfloxacin on the key fruit tree pest Grapholita molesta (oriental fruit moth). Our results showed that the antibiotic norfloxacin induced multiple developmental alterations by reducing the abundance of Enterobacteriaceae bacteria in the larval guts and adult ovaries: larval stage prolongation (+8.64 %), reduced pupal weight (-6.95 %), shortened adult period (-9.55 %), and impaired female fecundity with 24.77 % lower egg production and 16.57 % reduced egg hatchability. Our findings demonstrate that optimized antibiotic applications could simultaneously manage bacterial pathogens and suppress pest populations, providing dual agricultural benefits. This study proposes a novel integrated approach for orchard management through targeted antibiotic utilization.http://www.sciencedirect.com/science/article/pii/S014765132500658XGrapholita molestaAntibioticNorfloxacinGut microbiotaEnterobacteriaceaeReproduction |
| spellingShingle | Shaokai Liu Xueying Liu Donghan Wang Junjie Li Yanshen Fu Chunyang Guo Huilin Tang Junheng Gao Xiangqun Yuan Yiping Li Norfloxacin inhibited the growth, development and reproduction of Grapholita molesta by reducing the abundance of Enterobacteriaceae bacteria in the guts of larva and ovaries of female moth Ecotoxicology and Environmental Safety Grapholita molesta Antibiotic Norfloxacin Gut microbiota Enterobacteriaceae Reproduction |
| title | Norfloxacin inhibited the growth, development and reproduction of Grapholita molesta by reducing the abundance of Enterobacteriaceae bacteria in the guts of larva and ovaries of female moth |
| title_full | Norfloxacin inhibited the growth, development and reproduction of Grapholita molesta by reducing the abundance of Enterobacteriaceae bacteria in the guts of larva and ovaries of female moth |
| title_fullStr | Norfloxacin inhibited the growth, development and reproduction of Grapholita molesta by reducing the abundance of Enterobacteriaceae bacteria in the guts of larva and ovaries of female moth |
| title_full_unstemmed | Norfloxacin inhibited the growth, development and reproduction of Grapholita molesta by reducing the abundance of Enterobacteriaceae bacteria in the guts of larva and ovaries of female moth |
| title_short | Norfloxacin inhibited the growth, development and reproduction of Grapholita molesta by reducing the abundance of Enterobacteriaceae bacteria in the guts of larva and ovaries of female moth |
| title_sort | norfloxacin inhibited the growth development and reproduction of grapholita molesta by reducing the abundance of enterobacteriaceae bacteria in the guts of larva and ovaries of female moth |
| topic | Grapholita molesta Antibiotic Norfloxacin Gut microbiota Enterobacteriaceae Reproduction |
| url | http://www.sciencedirect.com/science/article/pii/S014765132500658X |
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