Development of alternative methodology for normalization of the small animals PET scanner of LIM/CDTN
Normalization is a step taken to correct variations in count rates between detection channels of small animals PET scanners. In general, in laboratory practice, normalization is performed using a commercial source of germanium 68. Given the half-life of the Ge-68 isotope, the normalization source mu...
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| Format: | Article |
| Language: | English |
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Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR)
2024-02-01
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| Series: | Brazilian Journal of Radiation Sciences |
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| Online Access: | https://bjrs.org.br/revista/index.php/REVISTA/article/view/2360 |
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| _version_ | 1849423852535283712 |
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| author | Anna Clara Moreira da Silva Victória Garcia Moreira Bruno Melo Mendes Rodrigo Modesto Gadelha Gontijo Andrea Vidal Ferreira |
| author_facet | Anna Clara Moreira da Silva Victória Garcia Moreira Bruno Melo Mendes Rodrigo Modesto Gadelha Gontijo Andrea Vidal Ferreira |
| author_sort | Anna Clara Moreira da Silva |
| collection | DOAJ |
| description | Normalization is a step taken to correct variations in count rates between detection channels of small animals PET scanners. In general, in laboratory practice, normalization is performed using a commercial source of germanium 68. Given the half-life of the Ge-68 isotope, the normalization source must be replaced every two years at most, which generates a significant spent for the Laboratory. The objective of this work was to develop and test an alternative rechargeable source to be used on normalization routine. The results indicated that the rechargeable source (18F-FDG) can be used to replace the commercial source. |
| format | Article |
| id | doaj-art-fa4117c172be45fe91b6d40888e186ac |
| institution | Kabale University |
| issn | 2319-0612 |
| language | English |
| publishDate | 2024-02-01 |
| publisher | Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR) |
| record_format | Article |
| series | Brazilian Journal of Radiation Sciences |
| spelling | doaj-art-fa4117c172be45fe91b6d40888e186ac2025-08-20T03:30:25ZengBrazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR)Brazilian Journal of Radiation Sciences2319-06122024-02-01121e2360e236010.15392/2319-0612.2024.23601983Development of alternative methodology for normalization of the small animals PET scanner of LIM/CDTNAnna Clara Moreira da Silva0Victória Garcia Moreira1Bruno Melo Mendes2Rodrigo Modesto Gadelha Gontijo3Andrea Vidal Ferreira4Centro de Desenvolvimento da Tecnologia Nuclear CDTN/CNEN Centro de Desenvolvimento da Tecnologia Nuclear CDTN/CNEN Centro de Desenvolvimento da Tecnologia Nuclear CDTN/CNENCNEN / UFMG / EBSERH – HCCentro de Desenvolvimento da Tecnologia Nuclear CDTN/CNEN Normalization is a step taken to correct variations in count rates between detection channels of small animals PET scanners. In general, in laboratory practice, normalization is performed using a commercial source of germanium 68. Given the half-life of the Ge-68 isotope, the normalization source must be replaced every two years at most, which generates a significant spent for the Laboratory. The objective of this work was to develop and test an alternative rechargeable source to be used on normalization routine. The results indicated that the rechargeable source (18F-FDG) can be used to replace the commercial source.https://bjrs.org.br/revista/index.php/REVISTA/article/view/2360normalizationge-68 source18f-fdgsmall animal pet scanner |
| spellingShingle | Anna Clara Moreira da Silva Victória Garcia Moreira Bruno Melo Mendes Rodrigo Modesto Gadelha Gontijo Andrea Vidal Ferreira Development of alternative methodology for normalization of the small animals PET scanner of LIM/CDTN Brazilian Journal of Radiation Sciences normalization ge-68 source 18f-fdg small animal pet scanner |
| title | Development of alternative methodology for normalization of the small animals PET scanner of LIM/CDTN |
| title_full | Development of alternative methodology for normalization of the small animals PET scanner of LIM/CDTN |
| title_fullStr | Development of alternative methodology for normalization of the small animals PET scanner of LIM/CDTN |
| title_full_unstemmed | Development of alternative methodology for normalization of the small animals PET scanner of LIM/CDTN |
| title_short | Development of alternative methodology for normalization of the small animals PET scanner of LIM/CDTN |
| title_sort | development of alternative methodology for normalization of the small animals pet scanner of lim cdtn |
| topic | normalization ge-68 source 18f-fdg small animal pet scanner |
| url | https://bjrs.org.br/revista/index.php/REVISTA/article/view/2360 |
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