Identification of cancer cell-intrinsic biomarkers associated with tumor progression and characterization of SFTA3 as a tumor suppressor in lung adenocarcinomas

Identification of cancer cell-intrinsic biomarkers associated with tumor progression and characterization of SFTA3 as a tumor suppressor in lung adenocarcinomas

Abstract Background Recent advancements in contemporary therapeutic approaches have increased the survival rates of lung cancer patients; however, the long-term benefits remain constrained, underscoring the pressing need for novel biomarkers. Surfactant-associated 3 (SFTA3), a long non-coding RNA pr...

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Bibliographic Details
Main Authors: Yu Zhao, Chengcheng Zhou, Ling Zuo, Haoming Yan, Yuhan Gu, Hong Liu, Guiping Yu, Xiaorong Zhou
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Cancer
Subjects:
Lung adenocarcinoma
Prognostic model
Single-cell RNA sequencing
Tumor microenvironment
SFTA3
Online Access:https://doi.org/10.1186/s12885-024-13395-z
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