The impact of socioeconomic disparities climate factors and antimicrobial stewardship on antimicrobial resistance in Africa
Abstract The issue of antimicrobial resistance (AMR) is of global significance, affecting both developed and underdeveloped nations. In the context of low- and middle-income countries (LMICs), in Africa and other regions confronted with worsening health inequities such as inadequate healthcare resou...
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| Language: | English |
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Springer
2025-05-01
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| Series: | Discover Public Health |
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| Online Access: | https://doi.org/10.1186/s12982-025-00631-5 |
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| author | Yousra A. El-Maradny Mark Anum Nortey Clyde M. Hakayuwa Ebuka Louis Anyamene J. Jenifer Florence Mary Stephen Tetteh Engmann Christopher Yao Tsikata Duaa Ashraf Ahmed Chizaram Onyeaghala Amira M. Heniedy Samwel Rema Gesaka Abdullahi Saminu Majani Edward |
| author_facet | Yousra A. El-Maradny Mark Anum Nortey Clyde M. Hakayuwa Ebuka Louis Anyamene J. Jenifer Florence Mary Stephen Tetteh Engmann Christopher Yao Tsikata Duaa Ashraf Ahmed Chizaram Onyeaghala Amira M. Heniedy Samwel Rema Gesaka Abdullahi Saminu Majani Edward |
| author_sort | Yousra A. El-Maradny |
| collection | DOAJ |
| description | Abstract The issue of antimicrobial resistance (AMR) is of global significance, affecting both developed and underdeveloped nations. In the context of low- and middle-income countries (LMICs), in Africa and other regions confronted with worsening health inequities such as inadequate healthcare resources and infrastructure, and a rising burden of infectious diseases, the adverse impact of antimicrobial resistance is exacerbated. This narrative review delves into the difficulties encountered in tackling the effects of AMR, focusing specifically on LMICs in Africa, where the overlap of climatic factors, socio-economic disparities, and inequities in access to healthcare intensifies the problem. The themes that emerged from the review include the need for infection prevention and control strategies, the adoption of a One Health approach to combat AMR, and the need for surveillance and monitoring. Several challenges were identified, including organizational and governmental issues, and the absence of leadership commitment. The review also emphasized the need for public and professional education for healthcare professionals and patients to promote and influence behavioral change patterns, a central aspect of AMR issues in Africa. These initiatives should be in tandem with enhanced diagnostic capacity, effective AMR surveillance, and capacity building at all levels of the healthcare system. Sustaining antimicrobial stewardship programs in Africa presents considerable obstacles, ranging from financial constraints to the lack of political will and coordinated efforts. When countries and partners adequately address these challenges by implementing sustainable solutions, LMICs in Africa can mitigate the threat of AMR, safeguard public health, and promote the responsible use of antimicrobials for future generations. |
| format | Article |
| id | doaj-art-fa3f7a830c33405f880beeb8a2cce933 |
| institution | DOAJ |
| issn | 3005-0774 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Springer |
| record_format | Article |
| series | Discover Public Health |
| spelling | doaj-art-fa3f7a830c33405f880beeb8a2cce9332025-08-20T03:09:35ZengSpringerDiscover Public Health3005-07742025-05-0122112110.1186/s12982-025-00631-5The impact of socioeconomic disparities climate factors and antimicrobial stewardship on antimicrobial resistance in AfricaYousra A. El-Maradny0Mark Anum Nortey1Clyde M. Hakayuwa2Ebuka Louis Anyamene3J. Jenifer Florence Mary4Stephen Tetteh Engmann5Christopher Yao Tsikata6Duaa Ashraf Ahmed7Chizaram Onyeaghala8Amira M. Heniedy9Samwel Rema Gesaka10Abdullahi Saminu11Majani Edward12Medical Biotechnology Department, Institute of Genetic Engineering and Biotechnology, City of Scientific Research and Technological Applications (SRTA-City)School of Public Health, University of GhanaDepartment of Public Health, Michael Chilufya Sata School of Medicine, Copperbelt UniversityCollege of Medicine, University of NigeriaDepartment of Community Medicine, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth UniversityFamily Medicine Unit, Manna Mission HospitalWest African Centre for Cell Biology of Infectious Pathogens, Department of Biochemistry, Cell and Molecular Biology, University of GhanaFaculty of Medicine, Ain Shams UniversityDepartment of Internal Medicine, University of Port Harcourt Teaching HospitalDepartment of Epidemiology, El-Beheira Veterinary Administration, Egyptian Ministry of AgricultureSchool of Public and Allied Health, UNICAF - Liverpool John Moores UniversityFaculty of Allied Health Sciences, Department of Environmental Health Science, Bayero UniversityDepartment of Public Health, St. Francis University College of Health and Allied SciencesAbstract The issue of antimicrobial resistance (AMR) is of global significance, affecting both developed and underdeveloped nations. In the context of low- and middle-income countries (LMICs), in Africa and other regions confronted with worsening health inequities such as inadequate healthcare resources and infrastructure, and a rising burden of infectious diseases, the adverse impact of antimicrobial resistance is exacerbated. This narrative review delves into the difficulties encountered in tackling the effects of AMR, focusing specifically on LMICs in Africa, where the overlap of climatic factors, socio-economic disparities, and inequities in access to healthcare intensifies the problem. The themes that emerged from the review include the need for infection prevention and control strategies, the adoption of a One Health approach to combat AMR, and the need for surveillance and monitoring. Several challenges were identified, including organizational and governmental issues, and the absence of leadership commitment. The review also emphasized the need for public and professional education for healthcare professionals and patients to promote and influence behavioral change patterns, a central aspect of AMR issues in Africa. These initiatives should be in tandem with enhanced diagnostic capacity, effective AMR surveillance, and capacity building at all levels of the healthcare system. Sustaining antimicrobial stewardship programs in Africa presents considerable obstacles, ranging from financial constraints to the lack of political will and coordinated efforts. When countries and partners adequately address these challenges by implementing sustainable solutions, LMICs in Africa can mitigate the threat of AMR, safeguard public health, and promote the responsible use of antimicrobials for future generations.https://doi.org/10.1186/s12982-025-00631-5Antimicrobial resistanceSuperbugAntimicrobial stewardshipSustainabilityClimate change |
| spellingShingle | Yousra A. El-Maradny Mark Anum Nortey Clyde M. Hakayuwa Ebuka Louis Anyamene J. Jenifer Florence Mary Stephen Tetteh Engmann Christopher Yao Tsikata Duaa Ashraf Ahmed Chizaram Onyeaghala Amira M. Heniedy Samwel Rema Gesaka Abdullahi Saminu Majani Edward The impact of socioeconomic disparities climate factors and antimicrobial stewardship on antimicrobial resistance in Africa Discover Public Health Antimicrobial resistance Superbug Antimicrobial stewardship Sustainability Climate change |
| title | The impact of socioeconomic disparities climate factors and antimicrobial stewardship on antimicrobial resistance in Africa |
| title_full | The impact of socioeconomic disparities climate factors and antimicrobial stewardship on antimicrobial resistance in Africa |
| title_fullStr | The impact of socioeconomic disparities climate factors and antimicrobial stewardship on antimicrobial resistance in Africa |
| title_full_unstemmed | The impact of socioeconomic disparities climate factors and antimicrobial stewardship on antimicrobial resistance in Africa |
| title_short | The impact of socioeconomic disparities climate factors and antimicrobial stewardship on antimicrobial resistance in Africa |
| title_sort | impact of socioeconomic disparities climate factors and antimicrobial stewardship on antimicrobial resistance in africa |
| topic | Antimicrobial resistance Superbug Antimicrobial stewardship Sustainability Climate change |
| url | https://doi.org/10.1186/s12982-025-00631-5 |
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