Influence of CD16 (FcγRIII) Expression on Peripheral Blood Mononuclear Cells on Response to Treatment with Rituximab in Pemphigus: A Cross-Sectional Study

Influence of CD16 (FcγRIII) Expression on Peripheral Blood Mononuclear Cells on Response to Treatment with Rituximab in Pemphigus: A Cross-Sectional Study

Background: Rituximab-mediated B-cell depletion in pemphigus patients is majorly caused by antibody-dependent cellular cytotoxicity. This is mediated by Fcγ receptors on immune cells, particularly FcγRIIIa (CD16) on natural killer (NK) cells. This study investigates the impact of FcγRIII expression...

Full description

Saved in:
Bibliographic Details
Main Authors: Ankur Sharma, Anshika Chauhan, Hitaishi Mehta, Sanjeev Handa, Naresh Sachdeva, Rahul Mahajan, Arnab Pal, Dipankar De
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-07-01
Series:Indian Dermatology Online Journal
Subjects:
cd16 expression
fcγ
receptors
fcγriiia (cd16)
fcγriiia genotypes
fcγriiia-158v/f polymorphism
monocytes
nk cells
nk-t cells
pemphigus
rituximab
remission
Online Access:https://journals.lww.com/10.4103/idoj.idoj_891_24
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items