Gene promoters are genomically encoded to facilitate histone exchange/incorporation.

Gene promoters are intrinsically hardwired not only to facilitate transcription preinitiation complex formation but also the release of paused RNA polymerase by H2A.Z. A new PLOS Biology study reveals poly (dA) tracts at promoters positively stimulate H2A.Z incorporation by the SWR complex in yeast.

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Main Author: Blaine Bartholomew
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-05-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3003160
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author Blaine Bartholomew
author_facet Blaine Bartholomew
author_sort Blaine Bartholomew
collection DOAJ
description Gene promoters are intrinsically hardwired not only to facilitate transcription preinitiation complex formation but also the release of paused RNA polymerase by H2A.Z. A new PLOS Biology study reveals poly (dA) tracts at promoters positively stimulate H2A.Z incorporation by the SWR complex in yeast.
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publisher Public Library of Science (PLoS)
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spelling doaj-art-fa3ae67bead34c9682fbb8dcc515b0d12025-08-20T02:33:15ZengPublic Library of Science (PLoS)PLoS Biology1544-91731545-78852025-05-01235e300316010.1371/journal.pbio.3003160Gene promoters are genomically encoded to facilitate histone exchange/incorporation.Blaine BartholomewGene promoters are intrinsically hardwired not only to facilitate transcription preinitiation complex formation but also the release of paused RNA polymerase by H2A.Z. A new PLOS Biology study reveals poly (dA) tracts at promoters positively stimulate H2A.Z incorporation by the SWR complex in yeast.https://doi.org/10.1371/journal.pbio.3003160
spellingShingle Blaine Bartholomew
Gene promoters are genomically encoded to facilitate histone exchange/incorporation.
PLoS Biology
title Gene promoters are genomically encoded to facilitate histone exchange/incorporation.
title_full Gene promoters are genomically encoded to facilitate histone exchange/incorporation.
title_fullStr Gene promoters are genomically encoded to facilitate histone exchange/incorporation.
title_full_unstemmed Gene promoters are genomically encoded to facilitate histone exchange/incorporation.
title_short Gene promoters are genomically encoded to facilitate histone exchange/incorporation.
title_sort gene promoters are genomically encoded to facilitate histone exchange incorporation
url https://doi.org/10.1371/journal.pbio.3003160
work_keys_str_mv AT blainebartholomew genepromotersaregenomicallyencodedtofacilitatehistoneexchangeincorporation