Gene promoters are genomically encoded to facilitate histone exchange/incorporation.

Gene promoters are intrinsically hardwired not only to facilitate transcription preinitiation complex formation but also the release of paused RNA polymerase by H2A.Z. A new PLOS Biology study reveals poly (dA) tracts at promoters positively stimulate H2A.Z incorporation by the SWR complex in yeast.

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Bibliographic Details
Main Author: Blaine Bartholomew
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-05-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3003160
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Summary:Gene promoters are intrinsically hardwired not only to facilitate transcription preinitiation complex formation but also the release of paused RNA polymerase by H2A.Z. A new PLOS Biology study reveals poly (dA) tracts at promoters positively stimulate H2A.Z incorporation by the SWR complex in yeast.
ISSN:1544-9173
1545-7885