Malaria parasite infection compromises control of concurrent systemic non-typhoidal Salmonella infection via IL-10-mediated alteration of myeloid cell function.

Malaria parasite infection compromises control of concurrent systemic non-typhoidal Salmonella infection via IL-10-mediated alteration of myeloid cell function.

Non-typhoidal Salmonella serotypes (NTS) cause a self-limited gastroenteritis in immunocompetent individuals, while children with severe Plasmodium falciparum malaria can develop a life-threatening disseminated infection. This co-infection is a major source of child mortality in sub-Saharan Africa....

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Bibliographic Details
Main Authors: Kristen L Lokken, Jason P Mooney, Brian P Butler, Mariana N Xavier, Jennifer Y Chau, Nicola Schaltenberg, Ramie H Begum, Werner Müller, Shirley Luckhart, Renée M Tsolis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004049&type=printable
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