Basic self-disorders may play a role in the development of depression in schizophrenia: a seven-year follow-up study
IntroductionDepression is the most common co-morbid psychiatric disorder in patients with schizophrenia and has a negative effect on functional outcomes and quality of life. There are several possible pathways leading to depressive symptoms in schizophrenia. Self-disorders are disturbances in the de...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1521366/full |
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| author | Elisabeth Haug Merete Glenne Øie Merete Glenne Øie Ingrid Hartveit Svendsen Ingrid Hartveit Svendsen Paul Møller Barnaby Nelson Barnaby Nelson Ingrid Melle Ingrid Melle |
| author_facet | Elisabeth Haug Merete Glenne Øie Merete Glenne Øie Ingrid Hartveit Svendsen Ingrid Hartveit Svendsen Paul Møller Barnaby Nelson Barnaby Nelson Ingrid Melle Ingrid Melle |
| author_sort | Elisabeth Haug |
| collection | DOAJ |
| description | IntroductionDepression is the most common co-morbid psychiatric disorder in patients with schizophrenia and has a negative effect on functional outcomes and quality of life. There are several possible pathways leading to depressive symptoms in schizophrenia. Self-disorders are disturbances in the deepest, pre-reflective level of the self and are suggested to be core features of schizophrenia. The relationship between self-disorders, and depressive symptoms has only been studied to a limited extent, and there are no longitudinal studies. This study aimed to explore the relationship between self-disorders at baseline and the development of depression over the follow-up periodMethodsSelf-disorders were examined with the Examination of Anomalous Self-Experience (EASE) instrument in 31 patients with schizophrenia during their first treatment. Seven years later we measured the total number of depressive episodes since the start of treatment.ResultsWe found a clear association between self-disorders at baseline and the total number of depressive episodes over the follow-up period.DiscussionSelf-disorders may play a role in the development of depression in schizophrenia. This may have implications for therapeutic approaches targeting a condition that is characterized by considerable suffering and an elevated risk of suicide. |
| format | Article |
| id | doaj-art-fa390fb2c6114281a8829ca29fb54a39 |
| institution | Kabale University |
| issn | 1664-0640 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Psychiatry |
| spelling | doaj-art-fa390fb2c6114281a8829ca29fb54a392025-01-08T06:12:06ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402025-01-011510.3389/fpsyt.2024.15213661521366Basic self-disorders may play a role in the development of depression in schizophrenia: a seven-year follow-up studyElisabeth Haug0Merete Glenne Øie1Merete Glenne Øie2Ingrid Hartveit Svendsen3Ingrid Hartveit Svendsen4Paul Møller5Barnaby Nelson6Barnaby Nelson7Ingrid Melle8Ingrid Melle9District Psychiatric Centre Gjøvik, Division of Mental Health Care, Innlandet Hospital Trust, Brumunddal, NorwayDepartment of Research, Innlandet Hospital Trust, Brumunddal, NorwayDepartment of Psychology, University of Oslo, Oslo, NorwayDepartment of competence and education, Innlandet Hospital Trust, Brumunddal, NorwayDepartment of Health Sciences, Norwegian University of Science and Technology Gjøvik, Gjøvik, NorwayDepartment of Mental Health Research and Development, Division of Mental Health and Addiction, Vestre Viken Hospital Trust, Drammen, NorwayCentre for Youth Mental Health, University of Melbourne, Parkville, VIC, AustraliaOrygen, Parkville, VIC, AustraliaAdult Psychiatry Department, Institute of Clinical Medicine, University of Oslo, Oslo, Norway0Section for Clinical Psychosis Research, Oslo University Hospital, Oslo, NorwayIntroductionDepression is the most common co-morbid psychiatric disorder in patients with schizophrenia and has a negative effect on functional outcomes and quality of life. There are several possible pathways leading to depressive symptoms in schizophrenia. Self-disorders are disturbances in the deepest, pre-reflective level of the self and are suggested to be core features of schizophrenia. The relationship between self-disorders, and depressive symptoms has only been studied to a limited extent, and there are no longitudinal studies. This study aimed to explore the relationship between self-disorders at baseline and the development of depression over the follow-up periodMethodsSelf-disorders were examined with the Examination of Anomalous Self-Experience (EASE) instrument in 31 patients with schizophrenia during their first treatment. Seven years later we measured the total number of depressive episodes since the start of treatment.ResultsWe found a clear association between self-disorders at baseline and the total number of depressive episodes over the follow-up period.DiscussionSelf-disorders may play a role in the development of depression in schizophrenia. This may have implications for therapeutic approaches targeting a condition that is characterized by considerable suffering and an elevated risk of suicide.https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1521366/fullschizophreniadepressionself-disorderspsychosisfollow-up, |
| spellingShingle | Elisabeth Haug Merete Glenne Øie Merete Glenne Øie Ingrid Hartveit Svendsen Ingrid Hartveit Svendsen Paul Møller Barnaby Nelson Barnaby Nelson Ingrid Melle Ingrid Melle Basic self-disorders may play a role in the development of depression in schizophrenia: a seven-year follow-up study Frontiers in Psychiatry schizophrenia depression self-disorders psychosis follow-up, |
| title | Basic self-disorders may play a role in the development of depression in schizophrenia: a seven-year follow-up study |
| title_full | Basic self-disorders may play a role in the development of depression in schizophrenia: a seven-year follow-up study |
| title_fullStr | Basic self-disorders may play a role in the development of depression in schizophrenia: a seven-year follow-up study |
| title_full_unstemmed | Basic self-disorders may play a role in the development of depression in schizophrenia: a seven-year follow-up study |
| title_short | Basic self-disorders may play a role in the development of depression in schizophrenia: a seven-year follow-up study |
| title_sort | basic self disorders may play a role in the development of depression in schizophrenia a seven year follow up study |
| topic | schizophrenia depression self-disorders psychosis follow-up, |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1521366/full |
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